In Vitro Evaluation of Cytotoxic and Pro-Apoptotic Effects of Hesperidin Alone and in Combination with Cisplatin on Human Malignant Melanoma Cell Line (A431)

In Vitro Evaluation of Cytotoxic and Pro-Apoptotic Effects of Hesperidin Alone and in Combination with Cisplatin on Human Malignant Melanoma Cell Line (A431)

<b>Background/Objectives:</b> Melanoma is an aggressive skin cancer with high metastatic potential and poor prognosis in advanced stages. Hesperidin, a natural flavonoid, has shown anticancer properties across various malignancies. This study aimed to evaluate the antiproliferative and p...

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Bibliographic Details
Main Authors: Mehmet Uğur Karabat, Mehmet Cudi Tuncer, İlhan Özdemir
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceuticals
Subjects:
melanoma
Hesperidin
apoptosis
caspase-3/7
MTT
Online Access:https://www.mdpi.com/1424-8247/18/6/854
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