Evolution of Resistant Mutants in <i>Pseudomonas aeruginosa</i> Persister Cells Under Meropenem Treatment

Evolution of Resistant Mutants in <i>Pseudomonas aeruginosa</i> Persister Cells Under Meropenem Treatment

Bacterial persisters are dormant cells that survive antibiotic treatment, serving as a reservoir for the emergence of resistant mutations. The evolution of antibiotic resistance poses a significant challenge to public health. In this study, we investigated the development of resistance in <i>P...

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Bibliographic Details
Main Authors: Jie Feng, Yifan Bian, Congjuan Xu, Zhihui Cheng, Yongxin Jin, Shouguang Jin, Weihui Wu
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Microorganisms
Subjects:
<i>Pseudomonas aeruginosa</i>
persister cells
antibiotic resistance
meropenem
evolutionary pathway
<i>oprD</i>
Online Access:https://www.mdpi.com/2076-2607/13/7/1672
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