Highly Effective mRNA-LNP Vaccine Against Respiratory Syncytial Virus (RSV) in Multiple Models

Highly Effective mRNA-LNP Vaccine Against Respiratory Syncytial Virus (RSV) in Multiple Models

Background: The transmembrane fusion (F) protein of RSV plays important roles in RSV pathogenesis as it mediates the fusion between the virus and the target cell membrane. During the fusion process, the F protein transits from a metastable state (prefusion, preF) to a stable state (postfusion, postF...

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Bibliographic Details
Main Authors: Huarong Bai, Xueliang Yu, Yue Gao, Qin Li, Baigang Wen, Rongkuan Hu
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Vaccines
Subjects:
respiratory vaccine
mRNA delivery
RSV
lipid nanoparticles
biomaterials
Online Access:https://www.mdpi.com/2076-393X/13/6/625
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