The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes

Aim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who sought treatment at outpatient clinic of Geria...

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Main Authors: Catarina Budyono, Siti Setiati, Dyah Purnamasari, Cleopas M Rumende
Format: Article
Language:English
Published: Interna Publishing 2016-09-01
Series:Acta Medica Indonesiana
Subjects:
Online Access:https://actamedindones.org/index.php/ijim/article/view/150
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author Catarina Budyono
Siti Setiati
Dyah Purnamasari
Cleopas M Rumende
author_facet Catarina Budyono
Siti Setiati
Dyah Purnamasari
Cleopas M Rumende
author_sort Catarina Budyono
collection DOAJ
description Aim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who sought treatment at outpatient clinic of Geriatry and Diabetes Division at Cipto Mangunkusumo Hospital between January and March 2016. Orthostatic hypotension was defined as a decrease in systolic blood pressure ≥20 mmHg and/or diastolic pressure ≥10 mmHg within 3 minutes after changing position from lying to standing. HbA1c levels was measured using Nycocard from Axis Shield. Chi square test was used for bivariate analysis and logistic regression was used for multivariate analysis against confounding variables. Results: the proportion of orthostatic hypotension in elderly subjects with DM was 27.4%. Median of HbA1c levels was higher in subjects with than without orthostatic hypotension (7.6% vs. 7.1%; p<0.05). There was an association between HbA1c levels of ≥7.35% and the incidence of orthostatic hypotension (OR 1.987, 95% CI 1.2-3.2). The duration of having DM was a confounding variable. Conclusion: orthostatic hypotension is more common in elderly subjects with DM. There is an association between the incidence of orthostatic hypotension and increased HbA1c levels in elderly patients with diabetes mellitus.
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spelling doaj-art-0d0ec2f8d54c40f28bc6b58742ea36a42025-07-24T07:02:48ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322016-09-01482The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with DiabetesCatarina Budyono0Siti Setiati1Dyah Purnamasari2Cleopas M Rumende3Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDivision of Geriatrics, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital. Jakarta, IndonesiaDivision of Endocrinology and Metaboism, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital. Jakarta, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, IndonesiaAim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who sought treatment at outpatient clinic of Geriatry and Diabetes Division at Cipto Mangunkusumo Hospital between January and March 2016. Orthostatic hypotension was defined as a decrease in systolic blood pressure ≥20 mmHg and/or diastolic pressure ≥10 mmHg within 3 minutes after changing position from lying to standing. HbA1c levels was measured using Nycocard from Axis Shield. Chi square test was used for bivariate analysis and logistic regression was used for multivariate analysis against confounding variables. Results: the proportion of orthostatic hypotension in elderly subjects with DM was 27.4%. Median of HbA1c levels was higher in subjects with than without orthostatic hypotension (7.6% vs. 7.1%; p<0.05). There was an association between HbA1c levels of ≥7.35% and the incidence of orthostatic hypotension (OR 1.987, 95% CI 1.2-3.2). The duration of having DM was a confounding variable. Conclusion: orthostatic hypotension is more common in elderly subjects with DM. There is an association between the incidence of orthostatic hypotension and increased HbA1c levels in elderly patients with diabetes mellitus.https://actamedindones.org/index.php/ijim/article/view/150diabetes mellituselderlyHbA1corthostatic hypotension
spellingShingle Catarina Budyono
Siti Setiati
Dyah Purnamasari
Cleopas M Rumende
The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes
Acta Medica Indonesiana
diabetes mellitus
elderly
HbA1c
orthostatic hypotension
title The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes
title_full The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes
title_fullStr The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes
title_full_unstemmed The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes
title_short The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes
title_sort proportion of orthostatic hypotension and its relationship with hba1c levels in elderly patients with diabetes
topic diabetes mellitus
elderly
HbA1c
orthostatic hypotension
url https://actamedindones.org/index.php/ijim/article/view/150
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