Swine Flu Progressive Pulmonary Fibrosis – Clinical Manifestation and Morphology of Explanted Lungs
Novel influenza A (H1N1) virus also known as swine flu results from the combination of genetic elements from swine, human, and avian viruses. During the 2009 swine flu pandemic, millions of people got infected with swine flu. Between April 2009 and April 2010, a large number of deaths were reported....
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2025-04-01
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Series: | Indian Journal of Transplantation |
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Online Access: | https://journals.lww.com/10.4103/ijot.ijot_125_24 |
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author | Shirish Sahebrao Chandanwale Madhuri Singh Akshi Raj Charusheela Gore Namit Gupta |
author_facet | Shirish Sahebrao Chandanwale Madhuri Singh Akshi Raj Charusheela Gore Namit Gupta |
author_sort | Shirish Sahebrao Chandanwale |
collection | DOAJ |
description | Novel influenza A (H1N1) virus also known as swine flu results from the combination of genetic elements from swine, human, and avian viruses. During the 2009 swine flu pandemic, millions of people got infected with swine flu. Between April 2009 and April 2010, a large number of deaths were reported. The virus is antigenetically distinct from seasonal influenza infection and is usually sensitive to oseltamivir. In recent years, sporadic cases of swine flu have been reported globally. There has been spurt in swine flu cases in India in recent years. Although a large number of swine flu patients present with acute respiratory distress syndrome, majority of these patients show complete recovery without leaving any residual illness. Few cases show residual fibrosis on high-resolution computed tomography after recovery. Even with high degree suspicion, clinical diagnosis is difficult. Confirmatory laboratory tests are essential for definitive diagnosis. We report a case of a 54-year-old female without any comorbidities who developed progressive pulmonary fibrosis and she required bilateral lung transplant. |
format | Article |
id | doaj-art-0c8e36ece4e64869be543e1e033ee104 |
institution | Matheson Library |
issn | 2212-0017 2212-0025 |
language | English |
publishDate | 2025-04-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Indian Journal of Transplantation |
spelling | doaj-art-0c8e36ece4e64869be543e1e033ee1042025-07-04T07:39:49ZengWolters Kluwer Medknow PublicationsIndian Journal of Transplantation2212-00172212-00252025-04-0119224324610.4103/ijot.ijot_125_24Swine Flu Progressive Pulmonary Fibrosis – Clinical Manifestation and Morphology of Explanted LungsShirish Sahebrao ChandanwaleMadhuri SinghAkshi RajCharusheela GoreNamit GuptaNovel influenza A (H1N1) virus also known as swine flu results from the combination of genetic elements from swine, human, and avian viruses. During the 2009 swine flu pandemic, millions of people got infected with swine flu. Between April 2009 and April 2010, a large number of deaths were reported. The virus is antigenetically distinct from seasonal influenza infection and is usually sensitive to oseltamivir. In recent years, sporadic cases of swine flu have been reported globally. There has been spurt in swine flu cases in India in recent years. Although a large number of swine flu patients present with acute respiratory distress syndrome, majority of these patients show complete recovery without leaving any residual illness. Few cases show residual fibrosis on high-resolution computed tomography after recovery. Even with high degree suspicion, clinical diagnosis is difficult. Confirmatory laboratory tests are essential for definitive diagnosis. We report a case of a 54-year-old female without any comorbidities who developed progressive pulmonary fibrosis and she required bilateral lung transplant.https://journals.lww.com/10.4103/ijot.ijot_125_24fibrosislungsprogressiveswine flutransplant |
spellingShingle | Shirish Sahebrao Chandanwale Madhuri Singh Akshi Raj Charusheela Gore Namit Gupta Swine Flu Progressive Pulmonary Fibrosis – Clinical Manifestation and Morphology of Explanted Lungs Indian Journal of Transplantation fibrosis lungs progressive swine flu transplant |
title | Swine Flu Progressive Pulmonary Fibrosis – Clinical Manifestation and Morphology of Explanted Lungs |
title_full | Swine Flu Progressive Pulmonary Fibrosis – Clinical Manifestation and Morphology of Explanted Lungs |
title_fullStr | Swine Flu Progressive Pulmonary Fibrosis – Clinical Manifestation and Morphology of Explanted Lungs |
title_full_unstemmed | Swine Flu Progressive Pulmonary Fibrosis – Clinical Manifestation and Morphology of Explanted Lungs |
title_short | Swine Flu Progressive Pulmonary Fibrosis – Clinical Manifestation and Morphology of Explanted Lungs |
title_sort | swine flu progressive pulmonary fibrosis clinical manifestation and morphology of explanted lungs |
topic | fibrosis lungs progressive swine flu transplant |
url | https://journals.lww.com/10.4103/ijot.ijot_125_24 |
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