Targeting alveolar epithelial cell metabolism in pulmonary fibrosis: Pioneering an emerging therapeutic strategy

Targeting alveolar epithelial cell metabolism in pulmonary fibrosis: Pioneering an emerging therapeutic strategy

Pulmonary fibrosis (PF) is a chronic and progressive lung disease, characterized by excessive deposition of fibrotic connective tissue within the lungs. Advances in transcriptomics, proteomics, and metabolomics have enhanced our understanding of PF’s pathogenesis. Recent studies have indicates that...

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Bibliographic Details
Main Authors: Tengkun Dai, Yidan Liang, Xin Li, Jiamin Zhao, Guangqin Li, Qihong Li, Lin Xu, Juanjuan Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
pulmonary fibrosis
metabolic reprogramming
alveolar epithelial cells
energy metabolism
pathogenesis
glucose metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1608750/full
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