Bridging the gaps in detection of structural cardiotoxicity in stem cell-derived cardiomyocytes: promise of miR-133b, miR-184 and miR-208b-3p

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Bridging the gaps in detection of structural cardiotoxicity in stem cell-derived cardiomyocytes: promise of miR-133b, miR-184 and miR-208b-3p

IntroductionDrug-induced cardiotoxicity is one of the main causes of attrition due to safety in preclinical and clinical development; therefore, identifying novel assays and/or biomarkers to detect potentially harmful candidates is pivotal for the pharmaceutical industry. Over the past decade, micro...

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Bibliographic Details
Main Authors:	M. Cherubin, A. Delaunois, J. P. Valentin, M. Alaerts, P. J. Guns, V. Gryshkova
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Pharmacology
Subjects:	hiPSC-CM structural cardiotoxicity biomarkers miRNA cardiotoxicity preclinical
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1584734/full
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