What is the optimal biological therapy for moderate to severe ulcerative colitis: a systematic review and network meta-analysis

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What is the optimal biological therapy for moderate to severe ulcerative colitis: a systematic review and network meta-analysis

ObjectiveThe biologics for moderate to severe ulcerative colitis (UC) have expanded with an increasing array. We performed an updated network meta-analysis to evaluate and compare the relative efficacy and safety profiles of biologics in moderate to severe UC.DesignWe searched literature to 18 May 2...

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Bibliographic Details
Main Authors:	Longbin Huang, Chen Kong, Ningning Yue, Hailan Zhao, Yuan Zhang, Chengmei Tian, Zhiliang Mai, Daoru Wei, Ruiyue Shi, Jun Yao, Lisheng Wang, Defeng Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Pharmacology
Subjects:	ulcerative colitis biological therapy clinical trials bayesian network meta-analysis systematic review
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1602024/full
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