Pathogen Enzyme-Mediated Alkoxyamine Homolysis as a Killing Mechanism of <i>Aspergillus fumigatus</i>

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Pathogen Enzyme-Mediated Alkoxyamine Homolysis as a Killing Mechanism of <i>Aspergillus fumigatus</i>

The emergence of antifungal-resistant <i>Aspergillus fumigatus (A. fumigatus)</i> became a serious public health concern, underscoring the need for new effective antifungal agents. Here, we present a strategy based on the in situ generation of radical species that are toxic to the pathog...

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Main Authors:	Marion Filliâtre, Pierre Voisin, Seda Seren, Ines Kelkoul, Olivier Glehen, Philippe Mellet, Sophie Thétiot-Laurent, Jean Menotti, Sylvain R. A. Marque, Gérard Audran, Abderrazzak Bentaher
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Journal of Fungi
Subjects:	alkoxyamine radical chemistry <i>Aspergillus fumigatus</i> dipeptidyl peptidase
Online Access:	https://www.mdpi.com/2309-608X/11/7/503
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