A spatiotemporal atlas of mouse gastrulation and early organogenesis to explore axial patterning and project in vitro models onto in vivo space

A spatiotemporal atlas of mouse gastrulation and early organogenesis to explore axial patterning and project in vitro models onto in vivo space

Summary: During gastrulation, mouse epiblast cells form the three germ layers that establish the body plan and initiate organogenesis. While single-cell atlases have advanced our understanding of lineage diversification, spatial aspects of differentiation remain poorly defined. Here, we applied spat...

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Bibliographic Details
Main Authors: Luke T.G. Harland, Tim Lohoff, Noushin Koulena, Nico Pierson, Constantin Pape, Farhan Ameen, Jonathan Griffiths, Bart Theeuwes, Nicola K. Wilson, Anna Kreshuk, Wolf Reik, Jennifer Nichols, Long Cai, John C. Marioni, Berthold Göttgens, Shila Ghazanfar
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Cell Reports
Subjects:
CP: Genomics
CP: Developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725008186
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