Increase of cell surface vimentin is associated with vimentin network disruption and subsequent stress-induced premature senescence in human chondrocytes
Accumulation of dysfunctional chondrocytes has detrimental consequences on the cartilage homeostasis and is thus thought to play a crucial role during the pathogenesis of osteoarthritis (OA). However, the underlying mechanisms of phenotypical alteration in chondrocytes are incompletely understood. H...
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Main Authors: | Jana Riegger, Rolf E Brenner |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2023-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/91453 |
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