A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis

Leiomyosarcoma is a rare mesenchymal tumor of smooth muscle origin and up to 5% is caused by vascular smooth muscle. Vascular leiomyosarcoma is more common in women. The disease is often caused by large veins. Depending on the localization of the vein, different clinical pictures may be seen. As it...

Full description

Saved in:
Bibliographic Details
Main Authors: Özlem Nuray Sever, Mehmet Sökücü
Format: Article
Language:English
Published: Galenos Publishing House 2019-04-01
Series:Journal of Oncological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S2452336418300918
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1839644307662831616
author Özlem Nuray Sever
Mehmet Sökücü
author_facet Özlem Nuray Sever
Mehmet Sökücü
author_sort Özlem Nuray Sever
collection DOAJ
description Leiomyosarcoma is a rare mesenchymal tumor of smooth muscle origin and up to 5% is caused by vascular smooth muscle. Vascular leiomyosarcoma is more common in women. The disease is often caused by large veins. Depending on the localization of the vein, different clinical pictures may be seen. As it is a rare tumor, there are difficulties in the clinical and pathological diagnosis of the disease. Standard recommendations on treatment are also not available.A 36-year-old female patient was admitted to our hospital with swelling in her left lower extremity. Physical examination of the patient was consistent with venous insufficiency findings. In the lower extremity venous doppler ultrasonography, there was grade 1 reflux in the left femoral vein. Medical treatment was performed. The patient was called for control after 1 month. The patient was re-admitted with deep vein thrombus. A repeat radiological examination revealed a mass in the left iliac vein. The patient was operated. The pathological diagnosis of the patient was evaluated in two centers. Finally, it was decided that the diagnosis was compatible with vascular leiomyosarcoma.Intravascular leiomyosarcoma can be overlooked in both clinical practice, radiological evaluation and histopathological examination because of its very rare occurrence. Keywords: Vascular leiomyosarcoma, Intravenous leiomyomatosis, Differential diagnosis
format Article
id doaj-art-092a513bffc741cbb2b83d84a4a11baf
institution Matheson Library
issn 2452-3364
language English
publishDate 2019-04-01
publisher Galenos Publishing House
record_format Article
series Journal of Oncological Sciences
spelling doaj-art-092a513bffc741cbb2b83d84a4a11baf2025-07-02T01:08:43ZengGalenos Publishing HouseJournal of Oncological Sciences2452-33642019-04-01514244A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosisÖzlem Nuray Sever0Mehmet Sökücü1Gaziantep University Faculty of Medicine, Department of Medical Oncology, Turkey; Corresponding author. Gaziantep University, School of Medicine, Department of Medical Oncology, Şahinbey, Gaziantep, Turkey.Sanko University Faculty of Medicine, Department of Pathology, TurkeyLeiomyosarcoma is a rare mesenchymal tumor of smooth muscle origin and up to 5% is caused by vascular smooth muscle. Vascular leiomyosarcoma is more common in women. The disease is often caused by large veins. Depending on the localization of the vein, different clinical pictures may be seen. As it is a rare tumor, there are difficulties in the clinical and pathological diagnosis of the disease. Standard recommendations on treatment are also not available.A 36-year-old female patient was admitted to our hospital with swelling in her left lower extremity. Physical examination of the patient was consistent with venous insufficiency findings. In the lower extremity venous doppler ultrasonography, there was grade 1 reflux in the left femoral vein. Medical treatment was performed. The patient was called for control after 1 month. The patient was re-admitted with deep vein thrombus. A repeat radiological examination revealed a mass in the left iliac vein. The patient was operated. The pathological diagnosis of the patient was evaluated in two centers. Finally, it was decided that the diagnosis was compatible with vascular leiomyosarcoma.Intravascular leiomyosarcoma can be overlooked in both clinical practice, radiological evaluation and histopathological examination because of its very rare occurrence. Keywords: Vascular leiomyosarcoma, Intravenous leiomyomatosis, Differential diagnosishttp://www.sciencedirect.com/science/article/pii/S2452336418300918
spellingShingle Özlem Nuray Sever
Mehmet Sökücü
A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis
Journal of Oncological Sciences
title A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis
title_full A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis
title_fullStr A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis
title_full_unstemmed A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis
title_short A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis
title_sort case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis
url http://www.sciencedirect.com/science/article/pii/S2452336418300918
work_keys_str_mv AT ozlemnuraysever acaseofvascularleiomyosarkomadiminishedwithintravenousleiomyomatosis
AT mehmetsokucu acaseofvascularleiomyosarkomadiminishedwithintravenousleiomyomatosis
AT ozlemnuraysever caseofvascularleiomyosarkomadiminishedwithintravenousleiomyomatosis
AT mehmetsokucu caseofvascularleiomyosarkomadiminishedwithintravenousleiomyomatosis