A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis
Leiomyosarcoma is a rare mesenchymal tumor of smooth muscle origin and up to 5% is caused by vascular smooth muscle. Vascular leiomyosarcoma is more common in women. The disease is often caused by large veins. Depending on the localization of the vein, different clinical pictures may be seen. As it...
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Galenos Publishing House
2019-04-01
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Series: | Journal of Oncological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2452336418300918 |
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author | Özlem Nuray Sever Mehmet Sökücü |
author_facet | Özlem Nuray Sever Mehmet Sökücü |
author_sort | Özlem Nuray Sever |
collection | DOAJ |
description | Leiomyosarcoma is a rare mesenchymal tumor of smooth muscle origin and up to 5% is caused by vascular smooth muscle. Vascular leiomyosarcoma is more common in women. The disease is often caused by large veins. Depending on the localization of the vein, different clinical pictures may be seen. As it is a rare tumor, there are difficulties in the clinical and pathological diagnosis of the disease. Standard recommendations on treatment are also not available.A 36-year-old female patient was admitted to our hospital with swelling in her left lower extremity. Physical examination of the patient was consistent with venous insufficiency findings. In the lower extremity venous doppler ultrasonography, there was grade 1 reflux in the left femoral vein. Medical treatment was performed. The patient was called for control after 1 month. The patient was re-admitted with deep vein thrombus. A repeat radiological examination revealed a mass in the left iliac vein. The patient was operated. The pathological diagnosis of the patient was evaluated in two centers. Finally, it was decided that the diagnosis was compatible with vascular leiomyosarcoma.Intravascular leiomyosarcoma can be overlooked in both clinical practice, radiological evaluation and histopathological examination because of its very rare occurrence. Keywords: Vascular leiomyosarcoma, Intravenous leiomyomatosis, Differential diagnosis |
format | Article |
id | doaj-art-092a513bffc741cbb2b83d84a4a11baf |
institution | Matheson Library |
issn | 2452-3364 |
language | English |
publishDate | 2019-04-01 |
publisher | Galenos Publishing House |
record_format | Article |
series | Journal of Oncological Sciences |
spelling | doaj-art-092a513bffc741cbb2b83d84a4a11baf2025-07-02T01:08:43ZengGalenos Publishing HouseJournal of Oncological Sciences2452-33642019-04-01514244A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosisÖzlem Nuray Sever0Mehmet Sökücü1Gaziantep University Faculty of Medicine, Department of Medical Oncology, Turkey; Corresponding author. Gaziantep University, School of Medicine, Department of Medical Oncology, Şahinbey, Gaziantep, Turkey.Sanko University Faculty of Medicine, Department of Pathology, TurkeyLeiomyosarcoma is a rare mesenchymal tumor of smooth muscle origin and up to 5% is caused by vascular smooth muscle. Vascular leiomyosarcoma is more common in women. The disease is often caused by large veins. Depending on the localization of the vein, different clinical pictures may be seen. As it is a rare tumor, there are difficulties in the clinical and pathological diagnosis of the disease. Standard recommendations on treatment are also not available.A 36-year-old female patient was admitted to our hospital with swelling in her left lower extremity. Physical examination of the patient was consistent with venous insufficiency findings. In the lower extremity venous doppler ultrasonography, there was grade 1 reflux in the left femoral vein. Medical treatment was performed. The patient was called for control after 1 month. The patient was re-admitted with deep vein thrombus. A repeat radiological examination revealed a mass in the left iliac vein. The patient was operated. The pathological diagnosis of the patient was evaluated in two centers. Finally, it was decided that the diagnosis was compatible with vascular leiomyosarcoma.Intravascular leiomyosarcoma can be overlooked in both clinical practice, radiological evaluation and histopathological examination because of its very rare occurrence. Keywords: Vascular leiomyosarcoma, Intravenous leiomyomatosis, Differential diagnosishttp://www.sciencedirect.com/science/article/pii/S2452336418300918 |
spellingShingle | Özlem Nuray Sever Mehmet Sökücü A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis Journal of Oncological Sciences |
title | A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis |
title_full | A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis |
title_fullStr | A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis |
title_full_unstemmed | A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis |
title_short | A case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis |
title_sort | case of vascular leiomyosarkoma diminished with intravenous leiomyomatosis |
url | http://www.sciencedirect.com/science/article/pii/S2452336418300918 |
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