Design and search for prospective diuretics (CA II Inhibitors) among aroylhydrazones of esters quinone oxime using in silico and in vivo methodology
The design and search for new selective inhibitors of CA II with a better pharmacological profile, which would cause minimal electrolyte disturbances in the body, remains an urgent problem of medical chemistry and pharmacology today. It is important that the discovered new classes of inhibitors do...
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Main Authors: | K.V. Sokolova, V.V. Stavytskyi, S.О. Konovalova, O.A. Podpletnya, S.I. Kovalenko, A.P. Avdeenko |
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Format: | Article |
Language: | English |
Published: |
Dnipro State Medical University
2022-12-01
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Series: | Medičnì Perspektivi |
Subjects: | |
Online Access: | https://journals.uran.ua/index.php/2307-0404/article/view/271120 |
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