Noninvasive Diagnostic Technique in Stenotic Coronary Atherosclerosis

Objective: to determine the sensitivity and specificity of combined stress echocardiography (EchoCG) using dipyri-damole and dobutamine in diagnosing and defining the extent of stenotic coronary lesions in coronary heart disease (CHD) in a group of critically ill patients who are unable to perform a...

Full description

Saved in:
Bibliographic Details
Main Authors: A. Yu. Vasilyev, N. N. Mikheyev, T. P. Makarova
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2005-12-01
Series:Общая реаниматология
Online Access:https://www.reanimatology.com/rmt/article/view/1213
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1839578573972701184
author A. Yu. Vasilyev
N. N. Mikheyev
T. P. Makarova
author_facet A. Yu. Vasilyev
N. N. Mikheyev
T. P. Makarova
author_sort A. Yu. Vasilyev
collection DOAJ
description Objective: to determine the sensitivity and specificity of combined stress echocardiography (EchoCG) using dipyri-damole and dobutamine in diagnosing and defining the extent of stenotic coronary lesions in coronary heart disease (CHD) in a group of critically ill patients who are unable to perform a physical exercise.Materials and methods: the study included 57 male patients with suspected acute coronary syndrome who underwent stress EchoCG using dipyridamole in high doses in combination with dobutamine, as well as coronary angiography.Results: stress EchoCG could bring up to the diagnostic criteria in all the patients, of whom 9 patients were found at coronary angiography to have no coronary lesion, 34 and 14 patients had one- and many-vessel lesions, respectively. The sensitivity and specificity of combined stress EchoCG were significantly higher than those of EchoCG used in the diagnosis of CHD.Conclusion: stress EchoCG using dipyridamole in combination with dobutamine is a highly informative safe noninvasive technique for diagnosing CHD, its helps to identify patients with atypical acute coronary syndrome and to form a group of patients to be subject to urgent coronarography and angiosurgical intervention. The pattern of segmental contractile disorders at the height of exercise during combined stress Echo-CG makes it possible to define the site of stenotic coronary atherosclerosis with 97.3% sensitivity and to diagnose many-vessel lesion with 100% sensitivity and 100%specificity.
format Article
id doaj-art-05d19c0679a44246a6514f76f68f53d7
institution Matheson Library
issn 1813-9779
2411-7110
language English
publishDate 2005-12-01
publisher Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
record_format Article
series Общая реаниматология
spelling doaj-art-05d19c0679a44246a6514f76f68f53d72025-08-04T10:40:36ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102005-12-0116656910.15360/1813-9779-2005-6-65-691213Noninvasive Diagnostic Technique in Stenotic Coronary AtherosclerosisA. Yu. Vasilyev0N. N. Mikheyev1T. P. Makarova2Department of Radiation Diagnosis, Moscow State Medical and Stomatological University, MoscowMain Clinical Hospital, Ministry of Internal Affairs of Russia, MoscowMain Clinical Hospital, Ministry of Internal Affairs of Russia, MoscowObjective: to determine the sensitivity and specificity of combined stress echocardiography (EchoCG) using dipyri-damole and dobutamine in diagnosing and defining the extent of stenotic coronary lesions in coronary heart disease (CHD) in a group of critically ill patients who are unable to perform a physical exercise.Materials and methods: the study included 57 male patients with suspected acute coronary syndrome who underwent stress EchoCG using dipyridamole in high doses in combination with dobutamine, as well as coronary angiography.Results: stress EchoCG could bring up to the diagnostic criteria in all the patients, of whom 9 patients were found at coronary angiography to have no coronary lesion, 34 and 14 patients had one- and many-vessel lesions, respectively. The sensitivity and specificity of combined stress EchoCG were significantly higher than those of EchoCG used in the diagnosis of CHD.Conclusion: stress EchoCG using dipyridamole in combination with dobutamine is a highly informative safe noninvasive technique for diagnosing CHD, its helps to identify patients with atypical acute coronary syndrome and to form a group of patients to be subject to urgent coronarography and angiosurgical intervention. The pattern of segmental contractile disorders at the height of exercise during combined stress Echo-CG makes it possible to define the site of stenotic coronary atherosclerosis with 97.3% sensitivity and to diagnose many-vessel lesion with 100% sensitivity and 100%specificity.https://www.reanimatology.com/rmt/article/view/1213
spellingShingle A. Yu. Vasilyev
N. N. Mikheyev
T. P. Makarova
Noninvasive Diagnostic Technique in Stenotic Coronary Atherosclerosis
Общая реаниматология
title Noninvasive Diagnostic Technique in Stenotic Coronary Atherosclerosis
title_full Noninvasive Diagnostic Technique in Stenotic Coronary Atherosclerosis
title_fullStr Noninvasive Diagnostic Technique in Stenotic Coronary Atherosclerosis
title_full_unstemmed Noninvasive Diagnostic Technique in Stenotic Coronary Atherosclerosis
title_short Noninvasive Diagnostic Technique in Stenotic Coronary Atherosclerosis
title_sort noninvasive diagnostic technique in stenotic coronary atherosclerosis
url https://www.reanimatology.com/rmt/article/view/1213
work_keys_str_mv AT ayuvasilyev noninvasivediagnostictechniqueinstenoticcoronaryatherosclerosis
AT nnmikheyev noninvasivediagnostictechniqueinstenoticcoronaryatherosclerosis
AT tpmakarova noninvasivediagnostictechniqueinstenoticcoronaryatherosclerosis