Necrotizing Fasciitis, as a Dramatic Complication of Infectious Diseases, Remains a Significant Challenge for Doctors.

Introduction: Fasciitis is an inflammation of the fascia, the connective tissue that surrounds muscles, blood vessels, and nerves, which can rapidly progress to necrosis of these structures, leading to life-threatening situations. It is a polymicrobial infection caused by bacterial agents, fungi, vi...

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Main Authors: Ermira Muco, Najada Como, Ylber Vata, Amarildo Blloshmi, Spiro Kacori, Anxhela Nikolla
Format: Article
Language:English
Published: Albanian Society for Trauma and Emergency Surgery 2025-07-01
Series:Albanian Journal of Trauma and Emergency Surgery
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Online Access:https://journal.astes.org.al/AJTES/index.php/AJTES/article/view/455
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author Ermira Muco
Najada Como
Ylber Vata
Amarildo Blloshmi
Spiro Kacori
Anxhela Nikolla
author_facet Ermira Muco
Najada Como
Ylber Vata
Amarildo Blloshmi
Spiro Kacori
Anxhela Nikolla
author_sort Ermira Muco
collection DOAJ
description Introduction: Fasciitis is an inflammation of the fascia, the connective tissue that surrounds muscles, blood vessels, and nerves, which can rapidly progress to necrosis of these structures, leading to life-threatening situations. It is a polymicrobial infection caused by bacterial agents, fungi, viruses, and parasites, resulting in septicemia, multiorgan failure, septic shock, and potentially death. The LRINEC score is a valuable tool in diagnosing necrotizing fasciitis (NF). Case Presentation: The patient is a 62-year-old woman with a history of Diabetes Mellitus type 2 and Bilinear Myelodysplasia, currently receiving high-dose corticosteroid therapy. She was recently diagnosed with Herpes Zoster affecting the S1, S2, S3, S4, and S5 dermatomes. Initially, she was treated for 8 days with antivirals and antibiotics for symptoms of fever, fatigue, and pain in the gluteal and lumbar regions. However, her condition worsened, prompting her readmission to the hospital, where she developed signs of sepsis. After imaging, laboratory tests, and consultations with surgeons, she was diagnosed with necrotizing fasciitis. Multidisciplinary management and complex therapy led to an excellent outcome. Conclusion: Necrotizing fasciitis presents a significant diagnostic challenge due to its rarity and its clinical resemblance to other critical conditions. It is an urgent pathology that requires not only surgical intervention but also immediate medical attention. It has always intrigued healthcare professionals both locally and internationally. Early diagnosis remains the primary challenge, and the management of these patients by experienced senior surgeons is crucial for successful outcomes.
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language English
publishDate 2025-07-01
publisher Albanian Society for Trauma and Emergency Surgery
record_format Article
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spelling doaj-art-04eb79d28d5f4b33b47da2e2bc0c750b2025-07-20T17:43:47ZengAlbanian Society for Trauma and Emergency SurgeryAlbanian Journal of Trauma and Emergency Surgery2521-87782616-49222025-07-019210.32391/ajtes.v9i2.455Necrotizing Fasciitis, as a Dramatic Complication of Infectious Diseases, Remains a Significant Challenge for Doctors.Ermira MucoNajada Como0Ylber Vata1Amarildo Blloshmi2Spiro Kacori3Anxhela Nikolla4Infectious Diseases Service, University Hospital Center “Mother Theresa” Tirana, AlbaniaGeneral Surgery Service, University Hospital “Shefqet Ndroqi”, Tirana, AlbaniaUniversity Hospital Centre "Mother Theresa"3Radiology Service, University Hospital Center “Mother Theresa”, Tirana, AlbaniaInfectious Diseases Service, University Hospital Center “Mother Theresa” Tirana, AlbaniaIntroduction: Fasciitis is an inflammation of the fascia, the connective tissue that surrounds muscles, blood vessels, and nerves, which can rapidly progress to necrosis of these structures, leading to life-threatening situations. It is a polymicrobial infection caused by bacterial agents, fungi, viruses, and parasites, resulting in septicemia, multiorgan failure, septic shock, and potentially death. The LRINEC score is a valuable tool in diagnosing necrotizing fasciitis (NF). Case Presentation: The patient is a 62-year-old woman with a history of Diabetes Mellitus type 2 and Bilinear Myelodysplasia, currently receiving high-dose corticosteroid therapy. She was recently diagnosed with Herpes Zoster affecting the S1, S2, S3, S4, and S5 dermatomes. Initially, she was treated for 8 days with antivirals and antibiotics for symptoms of fever, fatigue, and pain in the gluteal and lumbar regions. However, her condition worsened, prompting her readmission to the hospital, where she developed signs of sepsis. After imaging, laboratory tests, and consultations with surgeons, she was diagnosed with necrotizing fasciitis. Multidisciplinary management and complex therapy led to an excellent outcome. Conclusion: Necrotizing fasciitis presents a significant diagnostic challenge due to its rarity and its clinical resemblance to other critical conditions. It is an urgent pathology that requires not only surgical intervention but also immediate medical attention. It has always intrigued healthcare professionals both locally and internationally. Early diagnosis remains the primary challenge, and the management of these patients by experienced senior surgeons is crucial for successful outcomes. https://journal.astes.org.al/AJTES/index.php/AJTES/article/view/455Necrotizing fasciitissepsisinfectious diseasesherpes zosterdiabetes mellituscorticosteroid therapy
spellingShingle Ermira Muco
Najada Como
Ylber Vata
Amarildo Blloshmi
Spiro Kacori
Anxhela Nikolla
Necrotizing Fasciitis, as a Dramatic Complication of Infectious Diseases, Remains a Significant Challenge for Doctors.
Albanian Journal of Trauma and Emergency Surgery
Necrotizing fasciitis
sepsis
infectious diseases
herpes zoster
diabetes mellitus
corticosteroid therapy
title Necrotizing Fasciitis, as a Dramatic Complication of Infectious Diseases, Remains a Significant Challenge for Doctors.
title_full Necrotizing Fasciitis, as a Dramatic Complication of Infectious Diseases, Remains a Significant Challenge for Doctors.
title_fullStr Necrotizing Fasciitis, as a Dramatic Complication of Infectious Diseases, Remains a Significant Challenge for Doctors.
title_full_unstemmed Necrotizing Fasciitis, as a Dramatic Complication of Infectious Diseases, Remains a Significant Challenge for Doctors.
title_short Necrotizing Fasciitis, as a Dramatic Complication of Infectious Diseases, Remains a Significant Challenge for Doctors.
title_sort necrotizing fasciitis as a dramatic complication of infectious diseases remains a significant challenge for doctors
topic Necrotizing fasciitis
sepsis
infectious diseases
herpes zoster
diabetes mellitus
corticosteroid therapy
url https://journal.astes.org.al/AJTES/index.php/AJTES/article/view/455
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