Trends in lifetime risk and years of potential life lost from diabetes in the United States, 1997-2018.
<h4>Background</h4>Both incidence and mortality of diagnosed diabetes have decreased over the past decade. However, the impact of these changes on key metrics of diabetes burden-lifetime risk (LR), years of potential life lost (YPLL), and years spent with diabetes-is unknown.<h4>Me...
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0268805&type=printable |
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| author | Alain K Koyama Yiling J Cheng Ralph Brinks Hui Xie Edward W Gregg Annika Hoyer Meda E Pavkov Giuseppina Imperatore |
| author_facet | Alain K Koyama Yiling J Cheng Ralph Brinks Hui Xie Edward W Gregg Annika Hoyer Meda E Pavkov Giuseppina Imperatore |
| author_sort | Alain K Koyama |
| collection | DOAJ |
| description | <h4>Background</h4>Both incidence and mortality of diagnosed diabetes have decreased over the past decade. However, the impact of these changes on key metrics of diabetes burden-lifetime risk (LR), years of potential life lost (YPLL), and years spent with diabetes-is unknown.<h4>Methods</h4>We used data from 653,811 adults aged ≥18 years from the National Health Interview Survey, a cross-sectional sample of the civilian non-institutionalized population in the United States. LR, YPLL, and years spent with diabetes were estimated from age 18 to 84 by survey period (1997-1999, 2000-2004, 2005-2009, 2010-2014, 2015-2018). The age-specific incidence of diagnosed diabetes and mortality were estimated using Poisson regression. A multistate difference equation accounting for competing risks was used to model each metric.<h4>Results</h4>LR and years spent with diabetes initially increased then decreased over the most recent time periods. LR for adults at age 20 increased from 31.7% (95% CI: 31.2-32.1%) in 1997-1999 to 40.7% (40.2-41.1%) in 2005-2009, then decreased to 32.8% (32.4-33.2%) in 2015-2018. Both LR and years spent with diabetes were markedly higher among adults of non-Hispanic Black, Hispanic, and other races compared to non-Hispanic Whites. YPLL significantly decreased over the study period, with the estimated YPLL due to diabetes for an adult aged 20 decreasing from 8.9 (8.7-9.1) in 1997-1999 to 6.2 (6.1-6.4) in 2015-2018 (p = 0.02).<h4>Conclusion</h4>In the United States, diabetes burden is declining, but disparities by race/ethnicity remain. LR remains high with approximately one-third of adults estimated to develop diabetes during their lifetime. |
| format | Article |
| id | doaj-art-047a084bb2754eb2a7a01d7bcc898f13 |
| institution | Matheson Library |
| issn | 1932-6203 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-047a084bb2754eb2a7a01d7bcc898f132025-06-25T05:31:13ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01175e026880510.1371/journal.pone.0268805Trends in lifetime risk and years of potential life lost from diabetes in the United States, 1997-2018.Alain K KoyamaYiling J ChengRalph BrinksHui XieEdward W GreggAnnika HoyerMeda E PavkovGiuseppina Imperatore<h4>Background</h4>Both incidence and mortality of diagnosed diabetes have decreased over the past decade. However, the impact of these changes on key metrics of diabetes burden-lifetime risk (LR), years of potential life lost (YPLL), and years spent with diabetes-is unknown.<h4>Methods</h4>We used data from 653,811 adults aged ≥18 years from the National Health Interview Survey, a cross-sectional sample of the civilian non-institutionalized population in the United States. LR, YPLL, and years spent with diabetes were estimated from age 18 to 84 by survey period (1997-1999, 2000-2004, 2005-2009, 2010-2014, 2015-2018). The age-specific incidence of diagnosed diabetes and mortality were estimated using Poisson regression. A multistate difference equation accounting for competing risks was used to model each metric.<h4>Results</h4>LR and years spent with diabetes initially increased then decreased over the most recent time periods. LR for adults at age 20 increased from 31.7% (95% CI: 31.2-32.1%) in 1997-1999 to 40.7% (40.2-41.1%) in 2005-2009, then decreased to 32.8% (32.4-33.2%) in 2015-2018. Both LR and years spent with diabetes were markedly higher among adults of non-Hispanic Black, Hispanic, and other races compared to non-Hispanic Whites. YPLL significantly decreased over the study period, with the estimated YPLL due to diabetes for an adult aged 20 decreasing from 8.9 (8.7-9.1) in 1997-1999 to 6.2 (6.1-6.4) in 2015-2018 (p = 0.02).<h4>Conclusion</h4>In the United States, diabetes burden is declining, but disparities by race/ethnicity remain. LR remains high with approximately one-third of adults estimated to develop diabetes during their lifetime.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0268805&type=printable |
| spellingShingle | Alain K Koyama Yiling J Cheng Ralph Brinks Hui Xie Edward W Gregg Annika Hoyer Meda E Pavkov Giuseppina Imperatore Trends in lifetime risk and years of potential life lost from diabetes in the United States, 1997-2018. PLoS ONE |
| title | Trends in lifetime risk and years of potential life lost from diabetes in the United States, 1997-2018. |
| title_full | Trends in lifetime risk and years of potential life lost from diabetes in the United States, 1997-2018. |
| title_fullStr | Trends in lifetime risk and years of potential life lost from diabetes in the United States, 1997-2018. |
| title_full_unstemmed | Trends in lifetime risk and years of potential life lost from diabetes in the United States, 1997-2018. |
| title_short | Trends in lifetime risk and years of potential life lost from diabetes in the United States, 1997-2018. |
| title_sort | trends in lifetime risk and years of potential life lost from diabetes in the united states 1997 2018 |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0268805&type=printable |
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