STING regulates NETs formation by activating GSDMD in influenza viral pneumonia

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STING regulates NETs formation by activating GSDMD in influenza viral pneumonia

BackgroundViral pneumonia is the most common and lethal pandemic disease, but there are no broad-spectrum antiviral drugs with high genetic barriers to resistance. To elucidate the mechanisms of viral pneumonia progression and potential targets for its treatment.MethodsViral pneumonia models were in...

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Bibliographic Details
Main Authors:	Rongrong Huang, Ranran Chen, Lijuan Xing, Lianhao Wu, Wenwen Zhu, Junsong Jing, Ting Zhou, Yueguo Wu, Sheng Zhang, Zhenqiang You
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Immunology
Subjects:	viral pneumonia STING NETs GSDMD anti-inflammatory
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1598902/full
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