Ambroxol confers neuroprotection against scopolamine-induced Alzheimer’s-like pathology by modulating oxidative stress, neuroinflammation, and cognitive deficits via Nrf-2/JNK/GSK-3β signaling pathways

Ambroxol confers neuroprotection against scopolamine-induced Alzheimer’s-like pathology by modulating oxidative stress, neuroinflammation, and cognitive deficits via Nrf-2/JNK/GSK-3β signaling pathways

Alzheimer’s disease (AD) is the most common and costly chronic progressive neurodegenerative disorder, with the highest impact on public health worldwide. Pathological hallmarks of AD include progressive cognitive decline and memory impairment, dominantly mediated by oxidative neurodegeneration. Oxi...

Full description

Saved in:
Bibliographic Details
Main Authors: Waqas Ahmad, Kyonghwan Choe, Riaz Ahmad, Tae Ju Park, Myeong Ok Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
scopolamine
ambroxol
oxidative stress
neuroinflammation
synaptic dysfunction.
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1607289/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items