Raider of the lost N-glycans – Localizing rare and frequently overlooked IgG N-glycans with sulfation or bisecting LacNAc

Immunoglobulin G (IgG) is the most abundant immunoglobulin in human blood. Here it plays a central role in the immune system by recognizing antigens and mediating effector functions of the humoral immune defense. The role of IgG N-glycosylation in many of these processes is well known. However, low-...

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Bibliographic Details
Main Authors: Robert Burock, Léa Chuzel, Thilo Kähne, Udo Reichl, Erdmann Rapp, René Hennig
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1593708/full
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