Percutaneous Coronary Intervention on Saphenous Vein Graft in Second Generation Drug Eluting Stent Era
The aim of the study was to determine major adverse cardiac events (MACE) related to the percutaneous coronary intervention (PCI) on saphenous vein graft (SVG) with a second- generation drug eluting stents in patients with previous coronary artery bypass graft (CABG). The research was conducted a...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2024-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/481998 |
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| Summary: | The aim of the study was to determine major adverse cardiac events (MACE)
related to the percutaneous coronary intervention (PCI) on saphenous vein graft (SVG) with a second-
generation drug eluting stents in patients with previous coronary artery bypass graft (CABG).
The research was conducted as a unicenter retrospective observational study which analyzed consecutive
patients of both genders who had PCI on SVG from January 1, 2016 until June 30, 2019. The
aim was to investigate the occurrence of MACE defined as development of periprocedural myocardial
infarction, acute heart failure in the first 24 hours after PCI, unstable angina after PCI, periprocedural
stroke, contrast induced nephropathy, death, acute/subacute/late stent thrombosis, and target
lesion revascularization. The study included 97 consecutive patients. MACE was recorded in 20.6%
of patients, more often in patients with thrombolysis in myocardial infarction grade flow ≤2. High
thrombus burden (HTB) was detected in 44.3% of patients and it significantly contributed to the
development of MACE. In conclusion, PCI on SVG is a highly challenging procedure, especially in
patients with an acute coronary syndrome. In patients who have HTB recorded in SVG, the usage of
thrombus aspiration and distal protection device can reduce the frequency of no-reflow phenomenon
and consequential MACE. |
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| ISSN: | 0353-9466 1333-9451 |