Granulocyte-macrophage colony-stimulating factor increases tumor growth and angiogenesis directly by promoting endothelial cell function and indirectly by enhancing the mobilization and recruitment of proangiogenic granulocytes
Granulocyte-macrophage colony-stimulating factor has been widely used as an adjuvant therapy for cancer patients exhibiting myelosuppression induced by chemotherapy or radiotherapy. However, the effects of granulocyte-macrophage colony-stimulating factor on tumor growth, as well as its precise mecha...
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Main Authors: | Qiaowei Zheng, Xueqian Li, Xiaoliang Cheng, Ting Cui, Yingcheng Zhuo, Wenbin Ma, Xue Zhao, Peipei Zhao, Xuanlin Liu, Weiyi Feng |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2017-02-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317692232 |
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