Ozone rectal insufflation inhibits the development of atherosclerosis in ApoE−/−mice, which is mediated by the regulation of gut microbiota and metabolites

IntroductionAtherosclerotic cardiovascular disease is the world’s leading cause of death. Researches have proven that ozone therapy can effectively inhibit the development of atherosclerosis; however, the underlying mechanisms remain unclear. This study aims to explore how ozone rectal insufflation...

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Bibliographic Details
Main Authors: Ruihua Li, Yulin Wang, Xuelian Ji, Qi Han, Kang He, Haobin Zhao, Hongbo Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1597695/full
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