Combination therapy with amelotеx and compligamv in patients with osteoarthrosis

Objective: to study the efficiency of combined use of CompligamV (a vitamin B complex group) and Amelotex (meloxicam) in the complex treatment of osteoarthrosis (OA). Subjects and methods. Thirty patients (25 women and 5 men) aged 49 to 83 years with a disease history of 2 to 20 years (mean 6.8 year...

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Main Author: Tatyana Anatolyevna Vygovskaya
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2010-12-01
Series:Современная ревматология
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Online Access:https://mrj.ima-press.net/mrj/article/view/319
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author Tatyana Anatolyevna Vygovskaya
author_facet Tatyana Anatolyevna Vygovskaya
author_sort Tatyana Anatolyevna Vygovskaya
collection DOAJ
description Objective: to study the efficiency of combined use of CompligamV (a vitamin B complex group) and Amelotex (meloxicam) in the complex treatment of osteoarthrosis (OA). Subjects and methods. Thirty patients (25 women and 5 men) aged 49 to 83 years with a disease history of 2 to 20 years (mean 6.8 years) mainly with involvement of knee, ankle, and shoulder joints, X-ray stage II-IV disease (after A. Larsen). OA was complicated by reactive synovitis of the knee and ankle joints in 48.3% of the patients. The minimal course of therapy for OA was 15 days: Amelotex (15 mg, intramuscular) and CompligamV were concurrently administered for the first 5 days; CompligamV therapy was continued on the 6th to 15th days. Therapeutic effectiveness was evaluated from clinical changes ranging in 0 to 5 scores by the Oswestry questionnaire (rest pain, movement pain, and limited active and passive movements). A clinical relevant effect was stated when the scores in each section were decreased by 6 scores or more. Furthermore, the data from the health status scale, the pain intensity scale, and the risk for gastrointestinal complications were assessed by the Singh index. Results. There were clinical improvements (reduced signs of arthritis, increased exercise endurance, relieved pain syndrome) during combination therapy with Amelotex and CompligamV. Conclusion. The rapid onset and long duration of the action of combination therapy with Amelotex and CompligamV positively affected the patients' status and could reduce the cost of treatment
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spelling doaj-art-03953b0e9f9c4dc8a1c34b127de2751a2025-08-04T14:00:30ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2010-12-0144404210.14412/1996-7012-2010-6341624Combination therapy with amelotеx and compligamv in patients with osteoarthrosisTatyana Anatolyevna VygovskayaObjective: to study the efficiency of combined use of CompligamV (a vitamin B complex group) and Amelotex (meloxicam) in the complex treatment of osteoarthrosis (OA). Subjects and methods. Thirty patients (25 women and 5 men) aged 49 to 83 years with a disease history of 2 to 20 years (mean 6.8 years) mainly with involvement of knee, ankle, and shoulder joints, X-ray stage II-IV disease (after A. Larsen). OA was complicated by reactive synovitis of the knee and ankle joints in 48.3% of the patients. The minimal course of therapy for OA was 15 days: Amelotex (15 mg, intramuscular) and CompligamV were concurrently administered for the first 5 days; CompligamV therapy was continued on the 6th to 15th days. Therapeutic effectiveness was evaluated from clinical changes ranging in 0 to 5 scores by the Oswestry questionnaire (rest pain, movement pain, and limited active and passive movements). A clinical relevant effect was stated when the scores in each section were decreased by 6 scores or more. Furthermore, the data from the health status scale, the pain intensity scale, and the risk for gastrointestinal complications were assessed by the Singh index. Results. There were clinical improvements (reduced signs of arthritis, increased exercise endurance, relieved pain syndrome) during combination therapy with Amelotex and CompligamV. Conclusion. The rapid onset and long duration of the action of combination therapy with Amelotex and CompligamV positively affected the patients' status and could reduce the cost of treatmenthttps://mrj.ima-press.net/mrj/article/view/319osteoarthrosispaincombination therapyamelotexcompligamv
spellingShingle Tatyana Anatolyevna Vygovskaya
Combination therapy with amelotеx and compligamv in patients with osteoarthrosis
Современная ревматология
osteoarthrosis
pain
combination therapy
amelotex
compligamv
title Combination therapy with amelotеx and compligamv in patients with osteoarthrosis
title_full Combination therapy with amelotеx and compligamv in patients with osteoarthrosis
title_fullStr Combination therapy with amelotеx and compligamv in patients with osteoarthrosis
title_full_unstemmed Combination therapy with amelotеx and compligamv in patients with osteoarthrosis
title_short Combination therapy with amelotеx and compligamv in patients with osteoarthrosis
title_sort combination therapy with amelotеx and compligamv in patients with osteoarthrosis
topic osteoarthrosis
pain
combination therapy
amelotex
compligamv
url https://mrj.ima-press.net/mrj/article/view/319
work_keys_str_mv AT tatyanaanatolyevnavygovskaya combinationtherapywithamelotexandcompligamvinpatientswithosteoarthrosis