TREATMENT OF BREAST CANCER WITH METASTATIC CONTRALATERAL AXILLARY LYMPH NODES: CASE REPORT AND LITERATURE REVIEW
Background. until now, only a few reports have been available on clinical management of breast cancer patients with metastases to the contralateral axillary lymph nodes. Breast cancer is traditionally considered to affect ipsilateral lymph nodes. However, there are many reports describing cases with...
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2020-01-01
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| Series: | Сибирский онкологический журнал |
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| Online Access: | https://www.siboncoj.ru/jour/article/view/1241 |
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| author | V. A. Amosova A. V. Petrovsky M. V. Chernykh E. I. Kovalenko M. A. Frolova R. K. Valiev M. I. Nechushkin V. U. Kirsanov I. V. Vysotskaya D. E. Avtomonov |
| author_facet | V. A. Amosova A. V. Petrovsky M. V. Chernykh E. I. Kovalenko M. A. Frolova R. K. Valiev M. I. Nechushkin V. U. Kirsanov I. V. Vysotskaya D. E. Avtomonov |
| author_sort | V. A. Amosova |
| collection | DOAJ |
| description | Background. until now, only a few reports have been available on clinical management of breast cancer patients with metastases to the contralateral axillary lymph nodes. Breast cancer is traditionally considered to affect ipsilateral lymph nodes. However, there are many reports describing cases with contralateral axillary lymph node metastasis. Case presentation. We report a case of cancer in the right breast with contralateral axillary lymph node metastasis (Т2N1М1). Histological examination revealed invasive ductal G2 carcinoma with angiolymphatic invasion. No mutations in the BRca1, BRca2, cHEK2, and NBs1 genes were detected. the patient received complex treatment. Literature review. a PubMed search was conducted using the systematic review filter to identify articles describing cases with contralateral axillary lymph node metastasis. contralateral axillary lymph node metastasis, especially after surgery or radiotherapy, should be considered not only as hematogeneous metastasis but also as lymphagenous metastasis. survival of these patients is more comparable to that observed in patients with locally-advanced cancer than to that observed in patients with distant metastases. Conclusion. Early detection and management of contralateral axillary lymph node metastasis in breast cancer patients remains a debatable topic. Factors affecting disease prognosis have not been identified yet. Further studies concerning staging of contralateral axillary lymph node metastasis are needed. |
| format | Article |
| id | doaj-art-02bcdeb3e1a9424bb4f9ba290b9eef6d |
| institution | Matheson Library |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| publishDate | 2020-01-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj-art-02bcdeb3e1a9424bb4f9ba290b9eef6d2025-08-04T10:33:39ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682020-01-01186313810.21294/1814-4861-2019-18-6-31-38687TREATMENT OF BREAST CANCER WITH METASTATIC CONTRALATERAL AXILLARY LYMPH NODES: CASE REPORT AND LITERATURE REVIEWV. A. Amosova0A. V. Petrovsky1M. V. Chernykh2E. I. Kovalenko3M. A. Frolova4R. K. Valiev5M. I. Nechushkin6V. U. Kirsanov7I. V. Vysotskaya8D. E. Avtomonov9N.N. Blokhin National Medical Research Center of OncologyN.N. Blokhin National Medical Research Center of Oncology, First I.M. Sechenov Moscow State Medical UniversityOncoradiology Center PET-TechnologyN.N. Blokhin National Medical Research Center of OncologyN.N. Blokhin National Medical Research Center of OncologyN.N. Blokhin National Medical Research Center of OncologyN.N. Blokhin National Medical Research Center of OncologyFirst I.M. Sechenov Moscow State Medical UniversityFirst I.M. Sechenov Moscow State Medical UniversityFirst I.M. Sechenov Moscow State Medical UniversityBackground. until now, only a few reports have been available on clinical management of breast cancer patients with metastases to the contralateral axillary lymph nodes. Breast cancer is traditionally considered to affect ipsilateral lymph nodes. However, there are many reports describing cases with contralateral axillary lymph node metastasis. Case presentation. We report a case of cancer in the right breast with contralateral axillary lymph node metastasis (Т2N1М1). Histological examination revealed invasive ductal G2 carcinoma with angiolymphatic invasion. No mutations in the BRca1, BRca2, cHEK2, and NBs1 genes were detected. the patient received complex treatment. Literature review. a PubMed search was conducted using the systematic review filter to identify articles describing cases with contralateral axillary lymph node metastasis. contralateral axillary lymph node metastasis, especially after surgery or radiotherapy, should be considered not only as hematogeneous metastasis but also as lymphagenous metastasis. survival of these patients is more comparable to that observed in patients with locally-advanced cancer than to that observed in patients with distant metastases. Conclusion. Early detection and management of contralateral axillary lymph node metastasis in breast cancer patients remains a debatable topic. Factors affecting disease prognosis have not been identified yet. Further studies concerning staging of contralateral axillary lymph node metastasis are needed.https://www.siboncoj.ru/jour/article/view/1241breast cancercontralateral axillary lymphnode metastaseshematogeneous metastasis |
| spellingShingle | V. A. Amosova A. V. Petrovsky M. V. Chernykh E. I. Kovalenko M. A. Frolova R. K. Valiev M. I. Nechushkin V. U. Kirsanov I. V. Vysotskaya D. E. Avtomonov TREATMENT OF BREAST CANCER WITH METASTATIC CONTRALATERAL AXILLARY LYMPH NODES: CASE REPORT AND LITERATURE REVIEW Сибирский онкологический журнал breast cancer contralateral axillary lymph node metastases hematogeneous metastasis |
| title | TREATMENT OF BREAST CANCER WITH METASTATIC CONTRALATERAL AXILLARY LYMPH NODES: CASE REPORT AND LITERATURE REVIEW |
| title_full | TREATMENT OF BREAST CANCER WITH METASTATIC CONTRALATERAL AXILLARY LYMPH NODES: CASE REPORT AND LITERATURE REVIEW |
| title_fullStr | TREATMENT OF BREAST CANCER WITH METASTATIC CONTRALATERAL AXILLARY LYMPH NODES: CASE REPORT AND LITERATURE REVIEW |
| title_full_unstemmed | TREATMENT OF BREAST CANCER WITH METASTATIC CONTRALATERAL AXILLARY LYMPH NODES: CASE REPORT AND LITERATURE REVIEW |
| title_short | TREATMENT OF BREAST CANCER WITH METASTATIC CONTRALATERAL AXILLARY LYMPH NODES: CASE REPORT AND LITERATURE REVIEW |
| title_sort | treatment of breast cancer with metastatic contralateral axillary lymph nodes case report and literature review |
| topic | breast cancer contralateral axillary lymph node metastases hematogeneous metastasis |
| url | https://www.siboncoj.ru/jour/article/view/1241 |
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