Exploring the therapeutic mechanism of itraconazole combined with ritonavir on Candida albicans infection through network pharmacology and molecular docking

BackgroundAutophagy induced by itraconazole and ritonavir was found involved in the pathogenesis of C. albicans. This study was designed to explore the possible molecular mechanism of itraconazole and ritonavir in the treatment of Candida albicans infection through autophagy pathway.MethodsThe overl...

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Autores principales: Yiyang Feng, Wenli Feng, Jing Yang, Yan Ma
Formato: Artículo
Lenguaje:inglés
Publicado: Frontiers Media S.A. 2025-07-01
Colección:Frontiers in Pharmacology
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Acceso en línea:https://www.frontiersin.org/articles/10.3389/fphar.2025.1578749/full
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