Study of polymorphisms of UGT1A1 and DPYD genes in chemotherapy for colorectal cancer

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Study of polymorphisms of UGT1A1 and DPYD genes in chemotherapy for colorectal cancer

Background. The personalized approach implies an individual choice of medicines and their doses for the patient, providing the most effective and safe pharmacotherapy. Objective: analysis of the frequencies of UGT1A1 and DPYD polymorphisms and comparison of genotyping data with irinotecan and 5-fluo...

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Main Authors:	N. N. Timoshkina, O. A. Bogomolova, I. A. Zhuzhelenko, S. N. Kabanov, E. A. Kalabanova, I. S. Mitashok, Ya. V. Svetitskaya, D. I. Vodolazhskii
Format:	Article
Language:	Russian
Published:	Russian Academy of Sciences, Tomsk National Research Medical Center 2019-01-01
Series:	Сибирский онкологический журнал
Subjects:	colorectal cancer irinotecan 5-fluorouracil toxicity ugt1a1 dpyd ethnicity chemotherapy genotype
Online Access:	https://www.siboncoj.ru/jour/article/view/902
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