Study of the interaction of the GSB-106 BDNF neurotrophin dipeptide mimetic with the TrkB tyrosine kinase receptor using surface plasmon resonance technology
The interaction of the neurotrophin BDNF dipeptide mimetic, compound GSB-106, with the tyrosine kinase TrkB receptor specific for the fullsized neurotrophin was studied using surface plasmon resonance. The significant decrease in the binding of BDNF to TrkB, which was preincubated with GSB-106, was...
Saved in:
Main Authors: | A. V. Tarasiuk, Y. V. Mezentsev, O. V. Gnedenko, P. Yu. Povarnina, A. S. Ivanov |
---|---|
Format: | Article |
Language: | Russian |
Published: |
LLC “Publisher OKI”
2023-01-01
|
Series: | Фармакокинетика и Фармакодинамика |
Subjects: | |
Online Access: | https://www.pharmacokinetica.ru/jour/article/view/343 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Dimeric dipeptide mimetics of BDNF loop 4 are potential antidepressants with novel mechanisms of action
by: T. A. Gudasheva, et al.
Published: (2025-01-01) -
The mimetic of the brain neurotrophic factor GSB-106 has neuroprotective and neuroregenerative effects in experimental ischemic stroke
by: P. Yu. Povarnina, et al.
Published: (2022-05-01) -
Synthesis and the antidepressant-like activity investigation of bis-(N-monosuccinyl-D-seryl-D-lysine) hexamethylenediamide, the DD-enantiomer of the BDNF dipeptide mimetic, compound GSB-106
by: N. M. Sazonova, et al.
Published: (2024-11-01) -
BDNF/TrkB signaling in stable coronary artery disease
by: O. V. Atamas, et al.
Published: (2023-12-01) -
Effect of dexmedetomidine on hippocampal neuron development and BDNF-TrkB signal expression in neonatal rats
by: Lv J, et al.
Published: (2016-12-01)