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    YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2

    YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2 by Xia Zhao, Jinfeng Sun, Fan Chen, Hao Tang, Yuqing Zeng, Luyao Li, Qin Yu, Linjie Chen, Muzaffar Hammad, Xiaoxia Xu, Ziyao Meng, Wei Wang, Guang Liang

    Published 2025-07-01

    Abstract Background Parkinson's disease (PD) is a common neurodegenerative movement disorder, mainly characterized by the degeneration and loss of dopaminergic neurons in the substantia nigra. Oxidative stress is considered to be a key contributor to dopaminergic neuronal degeneration, triggeri...

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