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    Isodon lophanthoides alleviates liver fibrosis via modulation of purine metabolism and NF-κB signaling pathway: insights from multi-omics analysis

    Isodon lophanthoides alleviates liver fibrosis via modulation of purine metabolism and NF-κB signaling pathway: insights from multi-omics analysis 由 Kuikui Chen, Kuikui Chen, Kuikui Chen, Jie Liang, Jie Liang, Yong Tan, Yong Tan, Yaohua Li, Xiaojiao Pan, Xiaojiao Pan, Zhonghui Guo, Zhonghui Guo, Wentao Zhang, Zongxi Sun

    出版 2025-08-01

    BackgroundIsodon lophanthoides, a core botanical drug in Yao ethnomedicine, has traditionally been used to treat jaundice-type hepatitis and cholecystitis. However, its therapeutic potential and mechanisms against liver fibrosis remain largely unexplored.MethodsThe metabolites of I. lophanthoides wa...

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