Zoekresultaten - Zhiping Liu

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  1. 1
    RNF213 regulates blood‒brain barrier integrity by targeting TRAF3 for type I interferon activation during A. baumannii infection.

    RNF213 regulates blood‒brain barrier integrity by targeting TRAF3 for type I interferon activation during A. baumannii infection. door Yanfeng Li, Qingqing Xie, Luyu Yang, Qian Jiang, Zhiping Liu, Chengjiang Gao, Xiaopeng Qi, Tao Xu

    Gepubliceerd in 2025-07-01

    RNF213 is the first identified susceptibility gene for moyamoya disease, and the encoded protein was recently recognized as a key antimicrobial protein. However, the function of RNF213 in host defense against brain infection remains unclear. Here, we show that increased expression of Rnf213 is signi...

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  2. 2
    A comprehensive analysis of the tryptophan metabolism-related gene signature to predict the prognosis of esophageal squamous cell carcinoma based on multi-omics

    A comprehensive analysis of the tryptophan metabolism-related gene signature to predict the prognosis of esophageal squamous cell carcinoma based on multi-omics door Zhengjie Wu, Zhiping Liu, Yukun Wang, Geling Teng, Xiaodong Li, Tong Lu, Fangning Hu, Shuo Wu, Guanqiang Ma, Hua Zhang

    Gepubliceerd in 2025-08-01

    BackgroundTryptophan (Trp) metabolism plays a vital role in tumor development and outcomes. However, Trp in esophageal squamous cell carcinoma (ESCC) remains poorly understood. We aimed to explore the role and mechanism of Trp metabolism in ESCC.MethodsWe integrated single-cell RNA (scRNA) sequencin...

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  3. 3
    PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth

    PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth door Qingen Da, Yongfeng Cai, Qian Ma, Qiuhua Yang, Yapeng Cao, Yaqi Zhou, Dingwei Zhao, Zhiping Liu, Jiean Xu, Junming Quan, Liang Zhang, Rui Wang, Xuejun Jiang, Xiao Liu, Kunfu Ouyang, Zhen Han, Jikui Liu, Tao Wang, Chunxiang Zhang, Neal L. Weintraub, David J.R. Fulton, Jun Zhao, Mei Hong, Zigang Li, Yuqing Huo

    Gepubliceerd in 2025-08-01

    Summary: Aerobic glycolysis, termed the Warburg effect, is one of the aberrant metabolic pathways in highly proliferating cells. Glycolysis provides glycolytic metabolites to support the generation of biomass, such as nucleotides, amino acids, and lipids. Research on the direct interactions between...

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