Search Results - Zhe Jin
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Generative artificial intelligence in medical imaging: Current landscape, challenges, and future directions
Published 2025-07-01Get full textAbstract The clinical significance, digital attributes, and underlying high‐dimensional information in medical images make them a key area for the artificial intelligence (AI) revolution in health care. Generative AIs (GAIs) provide unprecedented abilities in synthesizing diverse and accurate simula...
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Glucose absorption in the duodenum is modulated by an estrogen receptor α-dependent regulation of glucose transporter functional expression
Published 2025-07-01Get full textIntroduction The mechanisms of estrogen in glucose metabolism are well established; however, the role of this hormone in glucose absorption remains unclear. In this study, we investigated the effects of estrogen on glucose absorption in humans, mice, and the human intestinal epithelium cell line SCB...
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Construction and interpretation of tobacco leaf position discrimination model based on interpretable machine learning
Published 2025-07-01Get full textTobacco leaf position is closely associated with its quality whose material basis is the chemical components of tobacco leaf. In recent years, near-infrared (NIR) spectroscopy combined with algorithmic models has emerged as a popular method for identifying the tobacco leaf position. However, when ap...
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Design, synthesis and biological evaluation of a novel class of indazole-containing compounds with potent anti-influenza activities targeting the PA-PB1 interface
Published 2025-06-01Get full textThe PA-PB1 interface of the influenza polymerase is an attractive site for antiviral drug design. In this study, we designed and synthesized a mini-library of indazole-containing compounds based on rational structure-based design to target the PB1-binding interface on PA. Biological evaluation of th...
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Radiomic Model Associated with Tumor Microenvironment Predicts Immunotherapy Response and Prognosis in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma
Published 2025-01-01Get full textBackground: No robust biomarkers have been identified to predict the efficacy of programmed cell death protein 1 (PD-1) inhibitors in patients with locoregionally advanced nasopharyngeal carcinoma (LANPC). We aimed to develop radiomic models using pre-immunotherapy MRI to predict the response to PD-...
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Artificial intelligence-augmented ultrasound diagnosis of follicular-patterned thyroid neoplasms: a multicenter retrospective studyResearch in context
Published 2025-08-01Get full textSummary: Background: Conventional diagnostic tools, including ultrasound, fine-needle aspiration cytology, and intraoperative frozen section pathology, may fail to reliably distinguish between benign and malignant FNs, leading to unnecessary or inadequate surgical interventions. We aimed to develop...
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