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    Identification of the T-box transcription factor t-bet in chickens and its role in immune response

    Identification of the T-box transcription factor t-bet in chickens and its role in immune response by Yuxin Guo, Zhaocan Zhou, Hui Gao, Shujun Zhang, Zhi Chen, He Chang, Hong Cao, Li Gao, Yongqiang Wang, Shijun J. Zheng

    Published 2025-10-01

    T-bet (T-box transcription factor TBX21), encoded by the Tbx21 gene, is a key regulator of T helper 1 (Th1) cell differentiation and cellular immunity. However, the role of T-bet in avian species remains elusive. To investigate the role of T-bet in avian immune response, we cloned chicken T-bet (chT...

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