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    Restoration of tendon repair microenvironment by grapefruit exosome-loaded microneedle system for tendinopathy therapy

    Restoration of tendon repair microenvironment by grapefruit exosome-loaded microneedle system for tendinopathy therapy by Yuan Zhang, Yuan Zhang, Ruiyang Zhang, Ti Zhang, Yuhao Mu, Talante Juma, Xu Li, Hao Li, Quanyi Guo, Yongping Cao

    Published 2025-07-01

    Tendinitis repair remains challenging due to the limited self-renewal capacity of tenocytes and persistent inflammatory microenvironment. Conventional therapies remain limited by systemic drug toxicity and fail to coordinate immunomodulation with matrix remodeling. Plant-derived extracellular vesicl...

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