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    Human-relevant doses of bisphenol a induce insulin resistance by downregulating Irs1 expression in skeletal muscle through estrogen receptor-α

    Human-relevant doses of bisphenol a induce insulin resistance by downregulating Irs1 expression in skeletal muscle through estrogen receptor-α by Zhang-Hong Ke, Yue-Hong Li, Ai-Li Yu, Xue-Fen Cai, Yan-Ying Lin, Shun-He Lin, Chu-Chu Zheng, Chen-Xi Yu, Bei-Hong Zheng, Yan Sun

    Published 2025-09-01

    Emerging evidence links bisphenol A (BPA) to insulin resistance, but the underlying mechanisms remain unclear. In this study, lactating mother mice and their male offspring post-weaning were exposed to bisphenol A (BPA) via drinking water at human-relevant (2.5 μg/L) and high human-relevant (25 μg/L...

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