Search Results - Yue Xu

BackgroundAtopic dermatitis (AD), a common chronic inflammatory skin disorder in children, often shows limited response to conventional therapies with potential adverse effects.MethodsThis real-world study evaluated dupilumab—a monoclonal antibody targeting IL-4/IL-13 signaling—in 59 Chinese pediatr...

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A compact high-speed active quenching and recharging circuit (AQRC) is proposed for single-photon avalanche diode (SPAD) detectors fabricated in standard 0.18 μm CMOS technology. A novel sensing and quenching scheme is employed to speed up the process of avalanche detection, en...

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<i>Background</i>: People with disabilities, particularly those from developing countries, often fare worse during disasters, pandemics, and other emergencies. China is located in the most disaster-prone region in the world. However, no study has examined emergency evacuation planning am...

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This letter proposes a behavioral model to estimate the statistical photon arrival time for time-of-flight (TOF) measurement circuit simulation. A theoretical model is derived to calculate the photon arrival rate by full consideration of a variety of properties of a TOF measurement system, such as l...

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The deteriorating physical and mental health of the rural elderly has become a common problem in developing countries and demands immediate attention. This article investigates the overall impact of China’s policy of community-based home care on rural elderly’s health, reveals the underlying mechani...

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This paper addresses the challenges of sample scarcity and class imbalance in remote sensing image semantic segmentation by proposing a decoupled synthetic sample generation framework based on a latent diffusion model. The method consists of two stages. In the label generation stage, we fine-tune a...

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The amyloid-beta 1-42 (Aβ1-42) oligomers are the most cytotoxic species of the amyloid family and play a key role in the pathology of Alzheimer’s Disease (AD). They have been shown to damage cellular membranes, but the exact mechanism is complex and not well understood. Multiple routes of membrane d...

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Abstract The Tibetan Plateau has substantial dynamic and thermal effects on regional and global climate, with plateau vortices (TPVs) playing a key role in summer precipitation. However, current land surface models often overlook the influence of gravel on soil hydrology and thermodynamics, which ma...

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The emotional well-being and welfare of urban residents are intricately linked to their surrounding living environments. Urban development in China has progressively placed greater emphasis on the human settlement environment. And has introduced policies such as urban regeneration and low-carbon com...

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Abstract Submarine magmatic–hydrothermal systems, where magmatic volatiles and fluids possibly serve as major sources of mineralization elements, have been extensively documented in numerous felsic‐hosted hydrothermal fields. Previous studies have primarily focused on the contribution of magmatic vo...

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Lasers are increasingly used in the biomedical field because of their concentrated energy, good stability, ease of use, and other advantages, promoting the development of precision medicine to a higher level. Medical laser equipment has transformed from a single therapeutic tool in an intelligent an...

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Various approaches have been explored to address the path planning problem for mobile robots. However, it remains a significant challenge, particularly in environments where a multi-tasking mobile robot operates alongside stochastically moving humans. This paper focuses on path planning for a mobile...

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Deficit irrigation is critical to global food production, particularly in arid and semi-arid regions with low precipitation. Given water shortage has threatened agricultural sustainability under the dry-land farming system in China, there is an urgent need to develop effective water-saving technolog...

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Gastric cancer (GC), a life-threatening malignancy with profound global health impacts, remains a cardinal focus of biomedical research. Recently, astragaloside IV (AS-IV), a bioactive triterpenoid saponin derived from Astragalus mongholicus Bunge, has garnered substantial attention for its multifac...

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Abstract Precipitation is a key driver of the global water cycle and energy circulation, yet its complex formation and dynamic lifecycle make both observation and simulation challenging. Tracking precipitation events and analyzing their lifecycle stages (development, maturity, and dissipation) are e...

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ObjectiveTo investigate whether Tuina therapy alleviated inflammation and motor neuron apoptosis in sciatic nerve injury (SNI) rats by regulating cytosolic phospholipase A2 (cPLA2) and Ras homolog family member A/Rho-associated coiled-coil comprising protein kinase 2 (RhoA/ROCK2) signaling cascades....

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Angiopoietin-like proteins (ANGPTLs) represent a family of secreted glycoproteins that are extensively expressed in vivo and are integral to various pathophysiological processes, including glucose and lipid metabolism, stem cell proliferation, local inflammation, vascular permeability, and angiogene...

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Accurate annotation of the medical image is the crucial step for image artificial intelligence (AI) clinical application. However, annotating medical image will incur a lot of annotation efforts and expense due to its high complexity and needing experienced doctors. In order to reduce the cost of an...

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