Αποτελέσματα αναζήτησης - Yu.M. Stepanov

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  1. 1

    Intraesophageal impedance-pH-manometry: general positions, clinical significance, clinical case analysis από Yu.M. Stepanov, I.Ya. Budzak

    Έκδοση 2025-06-01

    The article describes an innovative method for diagnosing gastroesophageal reflux disease — impedance-pH monitoring. The essence of the method, the equipment for its implementation, and the rules for preparing the patient for the examination are shown. The parameters for evaluating the results are a...

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  2. 2

    Features of eating behavior in children with different forms of non-alcoholic fatty liver disease από Yu.M. Stepanov, N.Yu. Zavhorodnia, O.Yu. Zavhorodnia

    Έκδοση 2021-09-01

     Aim – to study the features of the eating behavior (EB) in children with different forms of nonalcoholic fatty liver disease (NAFLD) - simple steatosis (SS) and nonalcoholic steatohepatitis (NASH), to compare the obtained data with the eating behavior of children without liver steatosis. 120 patie...

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  3. 3

    Features of interleukin-17 and interleukin-23 expression in patients with inflammatory bowel diseases από Yu.M. Stepanov, M.V. Stoikevych, O.M. Tatarchuk, T.S. Tarasova

    Έκδοση 2025-03-01

    Background. Inflammatory bowel disease (IBD) is a serious medical and social problem, which leads to a significant interest in the study of etiology, pathogenesis, development of diagnostic and therapeutic complexes. There is growing evidence that interleukin (IL) 17 and IL-23 are potent mediators o...

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  4. 4

    Improvement of liver fibrosis verification using new minimally invasive markers in patients with chronic diffuse liver diseases από Yu.M. Stepanov, V.I. Didenko, I.A. Klenina, O.M. Tatarchuk, O.P. Petishko

    Έκδοση 2022-12-01

    The aim of our research was to obtain new minimally invasive serum markers of fibrotic changes of liver in patients with chronic diffuse liver diseases of different etiology and compare them with traditional markers. 364 patients aged 30 to 66 years were examined: 221 women (60.7%) and 143 men (39....

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  5. 5

    The role of high-resolution manometry in the diagnosis of esophageal disorders (literature review and personal clinical observations) από Yu.M. Stepanov, N.V. Prolom, S.O. Tarabarov, O.M. Babii, I.M. Adamska

    Έκδοση 2025-06-01

    At present, clinical gastroenterology utilizes a number of high-precision methods for functional diagnosis of the esophagus and stomach, among which high-resolution manometry (HRM) holds a prominent place. This innovative technique enables a detailed assessment of esophageal function, particularly t...

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  6. 6

    Evaluation of the state of small intestinal microbiota, pro- and anti-inflammatory cytokines, short-chain fatty acids in metabolic dysfunction-associated steatotic liver disease in... από Yu.M. Stepanov, V.I. Didenko, I.A. Klenina, O.M. Tatarchuk, O.P. Petishko, R.M. Kyslova

    Έκδοση 2025-03-01

    Background. The intestinal microbiota and its metabolites have a significant impact on the pathophy­siology of liver diseases, it plays an important role in human metabolism, supports the intestinal mucosal barrier and interacts with the immune system. The COVID-19 epidemic has led to a significant...

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  7. 7

    Efficacy of liraglutide in patients with metabolic-associated steatotic liver disease in type 2 diabetes mellitus από Yu.M. Stepanov, O.V. Zinych, I.A. Klenina, K.O. Shyshkan-Shyshova, N.M. Kushnarоva

    Έκδοση 2025-06-01

    Background. The increasing incidence of metabolism-associated steatotic liver disease (MASLD) and type 2 diabetes prompts physicians to improve strategies for the diagnosis, prevention, and treatment of these metabolic conditions. Objective: to investigate the effects of glucagon-like peptide-1 rece...

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