Search Results - Yu. V. Marchenkov

Objective. To comparatively study the efficiency of respiratory support in patients with acute lung lesion, by applying BIPAP, SIMV, and aIPPV.Subjects. Twenty-six patients with acute lung lesion whose pattern included acute respiratory distress syndrome (n=16), pneumonia (и=6), and pneumonitis (n=4...

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Objective. To optimize the results of treatment in patients with acute respiratory failure (ARF) due to lung contusion, by using the methods of non-invasive mask respiratory support. Materials and methods. The study covered 31 patients with severe blunt chest injury, multiple costal fractures, and h...

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Objective: to comparatively study the efficiency of postoperative analgesia in patients with lung cancers, by using patient-controlled intravenous analgesia (PCIA), continuous epidural analgesia (EA) + PCIA, and intrapleural analgesia (IPA) + PCIA. Subjects and methods. Forty-six patients who had un...

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Objective. To comparatively study the efficiency of respiratory support using biphasic positive airway pressure (BIPAP), spontaneous intermittent mandatory ventilation (SIMV), and intermittent positive pressure ventilation (IPPV) in patients with acute lung injury (ALI) and concomitant pneumothorax....

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Objective: to study the efficiency of a lung opening maneuver in patients with acute lung injury (ALI) and concomitant pneumothorax, who were on biphasic positive airway pressure ventilation (BIPAP) and synchronized intermittent mandatory ventilation. Subject and methods. Seventy-three patients with...

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The paper generalizes the 15 years’ experience of the V. A. Negovsky Research Institute of General Reanimatology, Russian Academy of Medical Sciences, in conducting fundamental studies of the morphological, functional, and clinical patterns of the development of acute respiratory distress syndrome (...

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The incidence of fat embolism ranges from 0.5 to 30% in injuries with long and pelvic bone fractures; it also occurs in other diseases and conditions. Moreover, mortality accounts for 3 to 67%. There is still no clear idea on the pathogenesis, prevention, and treatment of fat embolism. This review g...

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The paper presents the results of using the fourth-generation cephalosporin maxicef in the treatment of 20 patients with nosocomial pneumonia and severe concomitant injury. A control group comprised 20 patients receiving a combination of ceftazidime and amikacin. The total efficiency of the antibact...

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Pulmonary hemorrhage is a severe complication that determines high mortality rates in various diseases and injuries. By reviewing the Russian and foreign literature and their many years’ experience, the authors depict current methods for the diagnosis and treatment of pulmonary hemorrhage. Action al...

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The purpose of the present investigation was to study the levels of triglycerides, cholesterol metabolism, a number of biochemical plasma parameters, and the elastic properties of the arterial wall in the late period in victims with severe mechanical injury (SMI) and impaired hemodynamics.Material a...

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Objective: to reveal early lung morphological changes after acidin-pepsin aspiration (a combination of hydrochloric acid and proteolytic enzyme). Material and methods. An experiment was made on 30 non-inbred albino male rats whose trachea acidin-pepsin solution (pH 1.2) was administered into. The ex...

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Objective: to evaluate the in vitro and in vivo effects of various infusion solutions on red blood cell rheology in the early posttraumatic period. Material and methods. The in vitro study assessed crystalloids, albumin, dextrans, modified gelatin, and different generations of hydroxyethyl starches...

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Objective: to determine the time and development rate of acute lung injury (ALI) in severe brain injury (SBI) complicated by aspiration of gastric contents or blood. Subjects and methods. Twenty-nine patients aged 19 to 70 years, who had isolated SBI, of whom there were 24 males and 5 females), were...

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The review presents the current view of the etiology and pathogenesis of hormonal and metabolic changes in critically ill patients. To build up a system accessible to clinicians to establish an early diagnosis of hypermetabolism syndrome will be able to make differential correction of endocrine and...

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Objective: to study lung morphological changes in a closed chest injury model in laboratory animals. Material and methods. Experiments were carried out in 30 male albino nonbred rats weighing 350—380 g. Closed chest injury was simulated, by exposing the chest of anesthetized rats to a 300-g metal cy...

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Objective: to study a number of free-radical reactions, the parameters of cholesterol exchange, and the extent of blood cell DNA damages in victims early after concomitant injury. Subjects and methods. The study covered 77 patients who had experienced severe mechanical injury. The patients&#8217...

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Aim: To compare the safety and efficacy of dexmedetomidine and haloperidol in patients with delirium and acute respiratory failure in non-invasive mask lung ventilation.Materials and methods. We carried out a retrospective analysis of data on patients with somatogenic delirium and acute respiratory...

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Objective: to reveal pulmonary morphological changes in acute lung injury (ALI) of varying etiology. Material and methods. An experiment was carried out on 4 groups of albino non-inbred male rats weighing 300—400 g. The following ALI models were 1) acidin-pepsin solution (PH-1.2) aspiration; 2) bloo...

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Objective: to reveal the patterns of blood biochemical changes, a trend in poikylocytosis, and impairment in the ultra-structure of red blood cells of the whole blood stored in citrate-phosphate-dextrose-adenine-1 during long-term storage. Material and methods. The whole blood that had been obtained...

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The paper describes a rare case of successful surgical treatment for mitral insufficiency due to heart valvular apparatus damage in the acute period of severe concomitant injury. Prosthetic mitral valve replacement was done on day 3 after injury. The patient was switched to spontaneous breathing on...

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