Search Results - Yu. N. Belenkov

The article discusses the limitations of the evidence from observational studies. Modern approaches to reducing bias in observational studies are discussed in detail, in particular, propensity score matching, which has become popular in recent years. The main differences between randomized and obser...

Full description

Aim. To study the long-term effect of complex therapy with enhanced external counterpulsation (EECP) on clinical parameters and outcomes in patients with stable coronary artery disease (CAD) complicated by heart failure (HF).Material and methods. The randomized trial EXCEL (Long-term Effects of enha...

Full description

Percutaneous coronary intervention (PCI) in coronary bifurcation stenosis is still regarded as technically complicated, due to the risk of lateral branch occlusion. Bifurcation stenosis is also characterised by higher intervention costs and restenosis incidence. Over the last 10 years, a range of ne...

Full description

Twenty centers from 19 Russian regions took part in ROSA 2, following the first ROSA study. Aim. In arterial hypertension (AH) patients, to compare efficacy, safety, and impact on cardiovascular event (CVE) incidence for two treatment strategies: intensive stepwise therapy with four classes of antih...

Full description

The article discusses the classification of heart failure (HF). A novel HF classification and its advantages over the existing ones are shown. Variants of approximate diagnoses are given in accordance with the novel HF classification.

The review presents modern views on pathogenetic mechanisms of myocardial hypertrophy, with the key role played by renin-angiotensin system (RAS) activation and hemodynamic overload. The authors analyze main structural and functional disturbances typical for and underlying the clinical manifestation...

Full description

The aim of review. To illuminate state-of-the-art of issue of ischemic heart disease and reflux-esophagitis combination and options of treatment of comorbide patients.Original positions. Ischemic heart disease (IHD) and reflux-esophagitis (RE) are one of the most frequent diseases of cardio-vascular...

Full description

In patients with coronary artery disease (CAD) and those who suffer from second type diabetes mellitus micro vascular disorders was found. Diabetes is associated with an increased risk of cardiovascular events. It might be due to micro vascular changes. We hypothesized that patients with CAD and CAD...

Full description

Aim. To study the long-term effect of complex therapy with enhanced external counterpulsation (EECP) on exercise tolerance, quality of life, and systolic cardiac function in patients with stable coronary artery disease (CAD) complicated by heart failure (HF).Material and methods. Open randomized stu...

Full description

Aim. In a non-randomised study, to assess middle-term (9 months) effectiveness and safety of percutaneous coronary intervention (PCI) with “Ephesos II” stent implantation. Material and methods. The study included 41 patients, treated at the Sani Konukoglu Medical Centre, Gaziantep, Turkey. Results....

Full description

Aim. To study the mid-term effects of enhanced external counterpulsation (EECP) in the structural and functional parameters of blood vessels, exercise tolerance and quality of life indicators in patients with verified coronary artery disease (CAD).Material and methods. Patients (n=70) with verified...

Full description

Aim. To study the effect of enhanced external counterpulsation (EECP) on the functional status, quality of life, structural and functional state of the vascular bed, and markers of glycemic control in patients with coronary artery disease (CAD) and type 2 diabetes mellitus (DM).Material and methods....

Full description

One of the clinical scenarios of hypertrophic cardiomyopathy (HCMP) is sudden cardiac death (SCD). The stratification of SCD risk is the key component of defining the therapeutic strategy in HCMP patients. Timely preventive treatment is the only life-saving intervention in patients with high SCD ris...

Full description

The prevalence of coronary heart disease (CHD) and type 2 diabetes mellitus (type 2 diabetes) in Russia and in the world continues to increase. Despite the prevention and optimization of therapy, CHD retains its leadership among all causes of death, and the mortality rate from type 2 diabetes and it...

Full description

Risk factors are the cornerstone of the cardiovascular continuum concept. Arterial hypertension is one of major risk factors, which accounts for a substantial proportion of cardiovascular morbidity and mortality due to cardiovascular complications (CVC). The latter develop due to, among other reason...

Full description

In patients with chronic heart failure (CHF), persistent neuro-humoral activation of sympatho-adrenal system and hyperglycaemia facilitate the activation of pro-cytokine inflammation component, as one of the pathophysiological mechanisms of endothelial dysfunction (ED). Aim. To study nebivolol effec...

Full description

Possibilities and prospects for the clinical use of enhanced external counterpulsation (EECP), which has long established itself throughout the world, are discussed in the article. Historical background, as well as the development stages of EECP for the treatment of patients with coronary heart dise...

Full description

Aim. To study the effect of various therapy regimens with enhanced external counterpulsation (EECP) on exercise tolerance, quality of life, indices of structural and functional state of cardiovascular system in patients with stable coronary artery disease (CAD) complicated by chronic heart failure (...

Full description

Chronic non- infectious diseases represent an important medical and social problem for the healthcare system. Optimal pharmacotherapy is not always effective enough, and the use of surgical treatment methods is not possible in all patients. In addition, an important link in the comprehensive managem...

Full description

Aim. To study the long-term effects of complex therapy with the addition of enhanced external counterpulsation (EECP) in patients with stable coronary artery disease (CAD) complicated by chronic heart failure (CHF).Material and methods. In the open randomized trial EXCEL (NCT05913778), 118 Patients...

Full description