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    A novel short transcript isoform of chicken IRF7 negatively regulates interferon-β production

    A novel short transcript isoform of chicken IRF7 negatively regulates interferon-β production door Yu-chen MA, Hua-yuan CHEN, Shen-yan GAO, Xiao-zhan ZHANG, Yong-tao LI, Xia YANG, Jun ZHAO, Zeng WANG

    Gepubliceerd in 2023-07-01

    Type I interferon (IFN-I) provides an important first line to protect avian species against pathogens invasion. IFN regulatory factor 7 (IRF7) has been identified as the most important regulator for both DNA and RNA virus-induced IFN-I production in chickens. Although four splicing variants of IRF7...

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