Torthaí cuardaigh - Yu-Li Lin
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Sodium-glucose co-transporter 2 inhibitors use and the risks of genital and urinary tract infection: What should we know?
Foilsithe / Cruthaithe 2025-07-01Faigh an téacs iomlánSodium-glucose co-transporter 2 (SGLT2) inhibitors have convincingly demonstrated efficacy in reducing cardiovascular (CV) and renal complications in patients with diabetes mellitus, chronic kidney disease, and heart failure. However, their use is also linked to the concern of some adverse events, t...
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Gut-derived uremic toxins and cardiovascular health in chronic kidney disease
Foilsithe / Cruthaithe 2025-07-01Faigh an téacs iomlánUremic toxins (UTs) are bioactive compounds that accumulate in chronic kidney disease (CKD) due to impaired renal clearance, exacerbating disease progression and cardiovascular (CV) complications. These toxins originate from endogenous metabolism, gut microbiota, and dietary intake and include prote...
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Serum <i>p</i>-Cresyl Sulfate Is Independently Associated with Aortic Stiffness in Non-Dialysis Chronic Kidney Disease Patients
Foilsithe / Cruthaithe 2025-07-01Faigh an téacs iomlán<i>p</i>-Cresyl sulfate (PCS), a gut-derived uremic toxin with proinflammatory and cytotoxic effects, has been implicated in cardiovascular injuries among patients with chronic kidney disease (CKD). Aortic stiffness (AS), assessed by carotid–femoral pulse wave velocity (cfPWV), is a reco...
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Serum Indoxyl Sulfate as a Potential Biomarker of Peripheral Arterial Stiffness in Patients with Non-Dialysis Chronic Kidney Disease Stages 3 to 5
Foilsithe / Cruthaithe 2025-06-01Faigh an téacs iomlánIndoxyl sulfate (IS), which is a protein-bound uremic toxin, is involved in vascular dysfunction and cardiovascular risk in subjects with chronic kidney disease (CKD). However, its role in peripheral arterial stiffness (PAS) remains unclear. This cross-sectional study evaluated the relationship betw...
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