Результаты поиска - Yu Zhou

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    The causal associations of 25(OH)D and its metabolites with oropharyngeal cancer risk: a Mendelian randomization study по YaoHui Yu, Yu Zhou

    Опубликовано 2025-07-01

    Background: Previous studies have suggested that there are distinct correlations of 25-hydroxyvitamin D (25(OH)D) and its metabolites with the risk of developing health conditions and cancer; however, the precise nature of these associations in patients with oropharyngeal cancer (OPC) is unknown. O...

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    A new species of Rhopalopsole (Insecta, Plecoptera, Leuctridae) from the Anhui Province of China and phylogeny of Leuctridae based on mitochondrial genomes по Xiao Yang, Yu-Zhou Du

    Опубликовано 2025-07-01

    A new species of Leuctridae (Plecoptera) from Anhui Province of China, Rhopalopsole gibba sp. nov., is described and illustrated. The new species is compared to a similar species, R. dicondylica Yang & Du, 2021. We sequenced the complete mitochondrial genome of the new species and found...

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    Outlier Detection and Explanation Method Based on FOLOF Algorithm по Lei Bai, Jiasheng Wang, Yu Zhou

    Опубликовано 2025-05-01

    Outlier mining constitutes an essential aspect of modern data analytics, focusing on the identification and interpretation of anomalous observations. Conventional density-based local outlier detection methodologies frequently exhibit limitations due to their inherent lack of data preprocessing capab...

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    Mutation graph of support $\tau $ -tilting modules over a skew-gentle algebra по Ping He, Yu Zhou, Bin Zhu

    Опубликовано 2025-01-01

    Let $\mathcal {D}$ be a Hom-finite, Krull-Schmidt, 2-Calabi-Yau triangulated category with a rigid object R. Let $\Lambda =\operatorname {End}_{\mathcal {D}}R$ be the endomorphism algebra of R. We introduce the notion of mutation of maximal rigid objects in the two-term subcategory...

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    Portfolio Model Considering Normal Uncertain Preference Relations of Investors по Yu Zhou, Chun Yan, Xiangrong Wang

    Опубликовано 2025-05-01

    The paper examines the application of uncertainty theory to portfolio decision making, specifically focusing on constructing portfolio models based on uncertain preference relations. Firstly, we establish the theoretical foundation by introducing the theory of uncertainty, which includes uncertain m...

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    Suicide attempts in elderly Han Chinese patients with major depressive disorder: prevalence and associated factors по Xiaofan Zhou, Yu Zhou, Xiang Yang Zhang

    Опубликовано 2025-09-01

    Objective: Suicide attempts (SA) are common in elderly patients with major depressive disorder (MDD), but few studies have focused on the prevalence and associated factors in elderly Chinese Han patients with MDD. Method: A total of 266 first episode and drug naïve older patients with MDD (age ≥ 50 ...

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    Molecular cloning and expression patterns of two small heat shock proteins from Chilo suppressalis (Walker) по Jie SONG, Ming-xing LU, Yu-zhou DU

    Опубликовано 2020-06-01

    Small heat shock proteins (sHSPs) are a very complex protein superfamily that increase insect temperature tolerance. In order to deeply understand the function and role of sHSPs in Chilo suppressalis (Walker), this study isolated and identified two CsHSP genes lacking introns from C. suppressalis, C...

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    Immune Checkpoint Inhibitor‐Based Therapy as the First‐Line Treatment for Advanced Non‐Small Cell Lung Cancer: Efficacy, Challenges, and Future Perspectives по Xingxiang Pu, Yu Zhou, Jingyi Wang, Lin Wu

    Опубликовано 2025-06-01

    ABSTRACT The selection of initial systemic treatment for advanced non‐small cell lung cancer (NSCLC) depends on histological subtypes, oncogenic driver identification through genomic profiling, and programmed death‐ligand 1 (PD‐L1) expression quantification. The choice of first‐line treatment is cru...

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    The APOE–Microglia Axis in Alzheimer’s Disease: Functional Divergence and Therapeutic Perspectives—A Narrative Review по Aiwei Liu, Tingxu Wang, Liu Yang, Yu Zhou

    Опубликовано 2025-06-01

    Apolipoprotein E (APOE) alleles play distinct roles in the pathogenesis of Alzheimer’s disease (AD), with <i>APOE</i>ε4 being the strongest genetic risk factor for late-onset AD, while <i>APOE</i>ε2 appears protective. Despite extensive research, the precise mechanisms by whi...

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    Synopsis of Chinese Alloperla Banks, 1906 (Plecoptera, Chloroperlidae), with description of a new species по Abdur Rehman, Qing-Bo Huo, Yu-Zhou Du

    Опубликовано 2025-07-01

    A new species of the genus Alloperla Banks, 1906 (Plecoptera, Chloroperlidae), Alloperla triquetra Rehman, Huo &amp;amp; Du, sp. nov., is described from Liaoning Province, China, with diagnostic features and color images of the adult habitus included. The terminalia of the new species are compar...

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    Correlation analysis of systemic immune-inflammation index values and arthritis risk in adults по Xuefei Xia, Yongyong Lou, Yu Zhou, Haoming Ling, Tingting Ge

    Опубликовано 2025-07-01

    Objective To investigate the correlation between systemic immune-inflammation index (SII) values and the risk of arthritis among adult participants. Methods Cross-sectional data from adult participants (aged ≥18 years) in the National Health and Nutrition Examination Survey 2011–2018 dataset were ut...

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    Staurosporine suppresses survival of HepG2 cancer cells through Omi/HtrA2-mediated inhibition of PI3K/Akt signaling pathway по Youming Ding, Bin Wang, Xiaoyan Chen, Yu Zhou, Jianhui Ge

    Опубликовано 2017-03-01

    Staurosporine, which is an inhibitor of a broad spectrum of protein kinases, has shown cytotoxicity on several human cancer cells. However, the underlying mechanism is not well understood. In this study, we examined whether and how this compound has an inhibitory action on phosphatidylinositol 3-kin...

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    Quantitative Evaluation of Sustainable Development and Eco-Environmental Carrying Capacity in Water-Deficient Regions: A Case Study in the Haihe River Basin, China по Zhong-gen WANG, Yu-zhou LUO, Ming-hua ZHANG, Jun XIA

    Опубликовано 2014-01-01

    Quantitative assessment of development sustainability could be a challenge to regional management and planning, especially for areas facing great risks of water shortage. Surface-water decline and groundwater over-pumping have caused serious environmental problems and limited economic development in...

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    No evidence for an effect of Wolbachia on mtDNA variation and evolution in natural populations of Sesamia inferens (Lepidoptera: Noctuidae) по Xiao-tian TANG, Jing XU, Ming-xing LU, Yu-zhou DU

    Опубликовано 2019-05-01

    Wolbachia are widespread maternally-inherited endosymbiotic bacteria that infect numerous arthropods. This study represents a thorough survey of the Wolbachia infection patterns in the pink stem borer, Sesamia inferens (Walker), an important rice pest in China, based on nucleotide comparisons for th...

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    Saxifraga stolonifera inhibits porcine epidemic diarrhea virus infection by disrupting nucleocapsid protein-p53 interaction по Hongde Lu, Hongde Lu, Haoyang Liu, Haoyang Liu, Ning Guo, Ning Guo, Yu Zhou, Yu Zhou, Haiyan Lu, Haiyan Lu, Zhiyuan He, Hong Dong, Hong Dong

    Опубликовано 2025-07-01

    Porcine epidemic diarrhea (PED) is an acute, highly contagious intestinal disease caused by the porcine epidemic diarrhea virus (PEDV), which has devastating effects on the global swine industry. Currently, no effective therapeutic agents have been identified for treating PEDV infections. Saxifraga...

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    Measurement-Device-Independent Quantum Random-Number Generator With Source Flaws по Tao Wu, Chun-Hui Zhang, Xing-Yu Zhou, Jian Li, Qin Wang

    Опубликовано 2023-01-01

    The measurement-device-independent quantum random number generator (MDI-QRNG) can resist all security loopholes on measurement devices, and it thus seems very promising in practical implementations. In the MDI-QRNG, sources are often assumed to be perfectly prepared, however, there inevitably exist...

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    Tumor-specific delivery of KRAS siRNA with iRGD-exosomes efficiently inhibits tumor growth по Yu Zhou, Yuan Yuan, Minghui Liu, Xiuting Hu, Yiming Quan, Xi Chen

    Опубликовано 2019-12-01

    Abstract Lung cancer is the major cause of cancer-related deaths globally. Mutant KRAS is a feature of 15–50% of lung cancer cases and represents one of the most prevalent oncogenic drivers in this disease. Unfortunately, although much effort has been spent on searching for small molecule inhibitors...

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    Methylation profile of bovine Oct4 gene coding region in relation to three germ layers по Xin-yu ZHOU, Liang-liang LIU, Wen-chao JIA, Chuan-ying PAN

    Опубликовано 2016-03-01

    Previous studies have shown that octamer-binding transcription factor 4 (Oct4) plays a significant role in early embryonic development of mammalian animals, and different Oct4 expression levels induce multi-lineage differentiation which are regulated by DNA methylation. To explore the relationship b...

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