תוצאות חיפוש - Yonggui Wu

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    ACSF2-PGK1 interaction promotes ferroptosis in renal tubular epithelial cells of diabetic nephropathy by regulating Keap1/Nrf2 signaling

    ACSF2-PGK1 interaction promotes ferroptosis in renal tubular epithelial cells of diabetic nephropathy by regulating Keap1/Nrf2 signaling מאת Xinran Liu, Chaoyi Chen, Sai Zhu, Xiaomei Luo, Li Gao, Ziyun Hu, Yu Ma, Ling Jiang, Yonggui Wu

    יצא לאור 2025-12-01

    Objectives Recent studies have highlighted the strong association between kidney disease and ferroptosis. However, the role of ferroptosis in diabetic nephropathy (DN) remains unclear. This study aimed to determine the role of ACSF2 in renal tubule injury in DN and its underlying mechanisms.Methods...

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    Diagnostic immune-related markers for diabetic kidney disease: a bioinformatics and machine learning approach

    Diagnostic immune-related markers for diabetic kidney disease: a bioinformatics and machine learning approach מאת Ying Wang, Xinyuan Zhou, Yuxin Jiang, Ling Jiang, Li Gao, Xueqi Liu, Xiaoxia Wang, Chenyu Sun, Yonggui Wu

    יצא לאור 2025-12-01

    Objective Diabetic kidney disease (DKD) is a leading cause of chronic kidney disease, with chronic inflammation driving its progression. This study aimed to identify immune-related diagnostic biomarkers for DKD and explore their association with immune cell infiltration.Methods Three glomerular tran...

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