Risultati della ricerca - Yingying Wang
-
1
microRNA-103 promotes LPS-induced inflammatory injury by targeting c-Myc in HK-2 cells
Pubblicazione 2019-12-01TestoAims microRNAs (miRNAs) occupy a vital position in diseases. This research aims to detect miR-103 influence on LPS-resulted HK-2 cells inflammation damage.Methods Cells were exposed to LPS for inducing injury. CCK-8 and flow cytometry were introduced to detect cell viability and apoptosis rate, resp...
Articolo -
2
Nurse-led weaning protocols—a systematic review and meta-analysis
Pubblicazione 2025-08-01TestoBackgroundResearch has demonstrated that protocol-directed weaning shortens the duration of mechanical ventilation (MV). Nurse-led weaning protocols have also been suggested to reduce MV duration in patients. Nevertheless, their implementation in mechanically ventilated patients is not widespread, a...
Articolo -
3
Silencing circular ANRIL protects HK-2 cells from lipopolysaccharide-induced inflammatory injury through up-regulating microRNA-9
Pubblicazione 2019-12-01TestoCircular antisense non-coding RNA in the INK4 locus (cANRIL) participated in inflammation of endothelial cells. However, whether cANRIL is associated with inflammatory injury of HK-2 cells, thereby affecting chronic kidney disease has not been investigated. We tested the hypothesis that cANRIL parti...
Articolo -
4
Effects of Salinity Fluctuation on Antimicrobial Resistance and Virulence Factor Genes of Low and High Nucleic Acid-Content Bacteria in a Marine Environment
Pubblicazione 2025-07-01TestoSalinity, as one of the critical environmental factors in marine ecosystems, has complex and wide-ranging biological effects. However, the effects of salinity fluctuation on antibiotic resistance genes (ARGs) and virulence factor genes (VFGs) in the marine environment are not well understood. In thi...
Articolo -
5
Mcart1 knockout enhances the level of macrophage inflammatory response in sepsis model mice
Pubblicazione 2025-05-01TestoObjective To investigate the effect of Mcart1 knockout on acute inflammation of macrophages in vitro and in vivo. Methods The Mcart1 knockout mice were used to establish a sepsis model induced by lipopolysaccharide(LPS), and the survival period was measured. Bone marrow derived macrophages(BMDM) of...
Articolo -
6
Correction: Baicalin-modifed polyethylenimine for miR-34a efficient and safe delivery
Pubblicazione 2025-07-01 Testo
Articolo -
7
Baicalin-modified polyethylenimine for miR-34a efficient and safe delivery
Pubblicazione 2023-11-01TestoThe security and efficiency of gene delivery vectors are inseparable for the successful construction of a gene delivery vector. This work provides a practical method to construct a charge-regulated, hydrophobic-modified, and functionally modified polyethylenimine (PEI) with effective gene delivery a...
Articolo -
8
fMRI insights into differential brain activation, executive function, and physical activity in older adults.
Pubblicazione 2025-01-01Testo<h4>Background</h4>Executive function is vital for cognitive health, particularly in older adults, where declines can lead to an increased risk of cognitive impairment. Physical activity (PA) has been linked to improvements in executive function, yet the underlying mechanisms remain poor...
Articolo -
9
LINC02679 regulates TRIML2 to promote gastric cancer proliferation and invasion via targeting miR-5004-3p
Pubblicazione 2025-08-01TestoAs a key protein, Tripartite motif family-like 2 (TRIML2) is crucial to the p53-mediated apoptosis and is correlated with tumorigenesis. Emerging evidence showed that long non-coding RNAs (lncRNAs) play roles in the malignant progression of gastric cancer (GC). However, the function and underlying m...
Articolo -
10
Biomimetic cartilage scaffold with orientated porous structure of two factors for cartilage repair of knee osteoarthritis
Pubblicazione 2019-12-01TestoA dual-layer biomimetic cartilage scaffold was prepared by mimicking the structural design, chemical cues and mechanical characteristics of mature articular cartilage. The surface layer was made from collagen (COL), chitosan (CS) and hyaluronic acid sodium (HAS). The transitional layer with microtub...
Articolo -
11
AhR deficiency exacerbates inflammation in diabetic wounds via impaired mitophagy and cGAS-STING-NLRP3 activation: Therapeutic potential of hydrogels loaded with FICZ
Pubblicazione 2025-10-01TestoDelayed healing of diabetic foot ulcers (DFUs) is driven by chronic inflammation and mitochondrial dysfunction. We identify the aryl hydrocarbon receptor (AhR) as a key regulator of immune and mitochondrial homeostasis in diabetic wounds. AhR expression was elevated in macrophages from human and mur...
Articolo -
12
Development of Gossypium hirsutum–Gossypium raimondii introgression lines and their use in QTL mapping of agricultural traits
Pubblicazione 2025-05-01TestoGossypium raimondii (2n=2x=26, D5), an untapped wild species, is the putative progenitor of the D-subgenome of G. hirsutum (2n=4x=52, AD1), an extensively cultivated species. Here, we developed a G. hirsutum (recipient)–G. raimondii (donor) introgression population to exploit the favorable QTLs/gene...
Articolo -
13
Biomimetic siRNA-METTL3 loading nanosystem alleviates myocardial hypertrophy by regulating the FASN and SCD1 m6A modification
Pubblicazione 2025-08-01TestoRNA m6A modification plays a vital role in regulating cardiac function; however, its comprehensive mechanisms require further exploration. We observed that the expression of METTL3, a m6A methyltransferase, is significantly increased in hypertrophic hearts as well as during phenylephrine (PE)-induce...
Articolo -
14
The Adoption of Chalcogenide Glass Fiber as Pulse Stretcher in an All-Fiber Structured 2 μm Chirped Pulse Amplification System
Pubblicazione 2021-01-01TestoWe present the development of an As<sub>2</sub>S<sub>3</sub> fiber-based reusable inline optical connector; and, for the first time to the best of our knowledge, integrated it into a 2 μm chirped pulse amplification system as the pulse stretcher. By this mechanism,...
Articolo