תוצאות חיפוש - Yingjun Li

The CRISPR-Cas system of Thermus thermophilus has emerged as a potent biotechnological tool, particularly its Cas6 endonuclease, which plays a crucial role in CRISPR RNA (crRNA) maturation. This protocol details a robust and reproducible method for the high-level expression and purification of recom...

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<b>Background</b>: African swine fever (ASF) is a highly contagious acute febrile disease with a near 100% mortality rate. There are currently no safe and effective vaccines for this disease. Cellular immunity plays an important role in the process of anti-viral, activating an effective...

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Long non-coding RNAs (lncRNAs) are widely transcribed in the genome, but their expression profile and roles in colorectal cancer are not well understood. The aim of this study was to investigate the long non-coding RNA expression profile in colorectal cancer and look for potential diagnostic biomark...

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Aims: The etiology of osteoarthritis (OA) remains unclear, involving a complex interaction of environmental and genetic factors. Observational studies have contributed substantially to identify modifiable risk factors that were associated with OA risk, but conclusions about the causality are hard to...

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This study investigates the efficacy of fermented corn straw as a viable corn substitute in rabbit diets, evaluating its impact on growth performance, intestinal health, cecal microbiota, and metabolite profiles to determine its potential for addressing corn shortages in animal husbandry. Over 35 da...

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BackgroundPrecise assessment of brain aging is crucial for early detection of neurodegenerative disorders and aiding clinical practice. Existing magnetic resonance imaging (MRI)–based methods excel in this task, but they still have room for improvement in capturing local morp...

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