Search Results - Ying Ying Sun

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  1. 1
    Digital spatial profiling of segmental outflow regions in trabecular meshwork reveals a role for ADAM15.

    Digital spatial profiling of segmental outflow regions in trabecular meshwork reveals a role for ADAM15. by Jennifer A Faralli, Mark S Filla, Yong-Feng Yang, Ying Ying Sun, Kassidy Johns, Kate E Keller, Donna M Peters, Donna M Peters

    Published 2024-01-01

    In this study we used a spatial transcriptomics approach to identify genes specifically associated with either high or low outflow regions in the trabecular meshwork (TM) that could potentially affect aqueous humor outflow in vivo. High and low outflow regions were identified and isolated from organ...

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    <i>SHROOM3</i> Deficiency Aggravates Adriamycin-Induced Nephropathy Accompanied by Focal Adhesion Disassembly and Stress Fiber Disorganization

    <i>SHROOM3</i> Deficiency Aggravates Adriamycin-Induced Nephropathy Accompanied by Focal Adhesion Disassembly and Stress Fiber Disorganization by Li-Nan Xu, Ying-Ying Sun, Yan-Feng Tan, Xin-Yue Zhou, Tian-Chao Xiang, Ye Fang, Fei Li, Qian Shen, Hong Xu, Jia Rao

    Published 2025-06-01

    <i>SHROOM3</i> encodes an actin-binding protein involved in kidney development and has been associated with chronic kidney disease through genome-wide association studies. However, its regulatory role in proteinuric kidney diseases and its mechanistic contributions to podocyte homeostasi...

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