Search Results - Yiming Hao

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  1. 1
    Discovery of wedelolactone from Eclipta Prostrata (L.) Linn. as a natural PDE4 inhibitor with potent anti-psoriasis effects

    Discovery of wedelolactone from Eclipta Prostrata (L.) Linn. as a natural PDE4 inhibitor with potent anti-psoriasis effects by Lingyu Wu, Yingying Wu, Shangding Yang, Siyu Jin, Qing Zhang, Zhongbin Cheng, Chaohui Wu, Yiming Hao, Ling Sun, Wenwen Liu, Donglei Shi, Jian Li, Yi-You Huang, Baoli Li, Hai-Bin Luo

    Published 2025-04-01

    Psoriasis is a chronic inflammatory disorder for which phosphodiesterase-4 (PDE4) inhibitors have emerged as promising therapeutic agents due to an ability to regulate inflammatory signaling pathways. In this study 1200 methanolic extracts from Chinese medicinal plants were screened and Eclipta pro...

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    Neonatal-Inspired Reprogramming of Microglial Pan-Programmed Cell Death Enhances Regeneration in Adult Spinal Cord Injury

    Neonatal-Inspired Reprogramming of Microglial Pan-Programmed Cell Death Enhances Regeneration in Adult Spinal Cord Injury by Beibei Yu, Yongfeng Zhang, Yujie Yang, Shijie Yang, Haining Wu, Xue Gao, Yiming Hao, Shengyou Li, Bing Xia, Jintao Liu, Lingli Guo, Borui Xue, Mingze Qin, Huangtao Chen, Jianzhong Li, Shouping Gong, Teng Ma, Jinghui Huang

    Published 2025-01-01

    In adult mammals, programmed cell death (PCD) facilitates tissue remodeling and regeneration in spinal cord injury (SCI), but excessive activation impedes SCI repair. However, no comprehensive pan-PCD atlas exists that encompasses diverse cell death patterns to fully elucidate PCD in adult SCI and d...

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