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    Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity

    Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity by Yong Zhang, Yesheng Fu, Lihua Qiang, Mengyuan Zhao, Zhe Lu, Zhuo Zhao, Guoping Chen, Zehui Lei, Qiyao Chai, Pupu Ge, Bingxi Li, Jing Wang, Cui Hua Liu, Lingqiang Zhang

    Published 2025-07-01

    Abstract The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon gene protein (STING) signaling plays a critical role in innate immunity and must be tightly regulated to maintain immune homeostasis, but the mechanism underlying the spatiotemporal regulation of this pathway remains largely elusiv...

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