Результаты поиска - Ye H
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Synthesis, structure and properties of 7-((4-amino-5-thio-1,2,4-triazole-3-yl)methyl)-theophylline derivatives по A. S. Hotsulia, Ye. H. Knysh
Опубликовано 2020-08-01The combination of derivatives of 1,2,4-triazole and theophylline creates fertile soil for biologically active substances. The use of these heterocyclic systems allows the use of simple chemical modification methods and available reagents. This determines the relevance of the chosen direction of sci...
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National market of diagnostic tests and test systems по T. S. Brytanova, A. V. Samko, Ye. H. Knysh
Опубликовано 2020-11-01The aim of the work was to analyze the market of diagnostic tests and test systems that are in circulation in Ukraine. Materials and methods. To achieve this goal, electronic and paper official sources of information were used, as well as pharmacy websites. The search, analytical, systematic, com...
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Research on the motivation of pharmaceutical workers in pharmacies по T. P. Zarichna, T. S. Brytanova, T. S. Raikova, Ye. H. Knysh
Опубликовано 2020-05-01The purpose of work was to study the motivating and demotivating factors of the activity of pharmaceutical staff and the conditions of increasing their work activity. Materials and methods. The material for our research was statistically processed information that was obtained during the survey o...
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A study of acute toxicity of newly synthesized compound on adult hydrobiont Danio rerio по A. A. Safonov, Yu. V. Karpenko, Ye. H. Knysh
Опубликовано 2021-03-01From ancient times the people used different poisons as a treatment for diseases of different genesis. To date, almost nothing has changed. One of the main conditions for the development of a new drug is its low toxicity. Literature analysis has shown that 1,2,4-triazole-3-thione derivatives are low...
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Acute toxicity of 2-(5-(adamantane-1-yl)-4R-1,2,4-triazole-3-ylthio) of the acetic acids and their salts’ derivatives по V. M. Odyntsova, O. I. Panasenko, Ye. H. Knysh
Опубликовано 2015-12-01Aim. To study the acute toxicity of 2-(5-(adamantane-1-yl)-4R-1,2,4-triazole-3-ylthio) acetic acids and their salts’ derivatives. Methods and results. According to the data the acute toxicity of investigated substances belongs to the 4th class of toxicity and they are low-toxic, their LD50 ranges...
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Preoperative Neutrophil-to-Albumin Ratio as a Prognostic Indicator in Advanced Gastric Cancer Undergoing Radical Gastrectomy по Ye H, Kang R, Chen M, Zhang S, Yang J
Опубликовано 2025-07-01Huaping Ye,1,* Rong Kang,2,* Mao Chen,3 Si Zhang,3 Jinfeng Yang1 1Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China; 2Department of Urology, The First Affiliated Hospital of Chengdu Medical Co...
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Market analysis of dietary supplements that affect the respiratory function по A. S. Hotsulia, O. O. Mikolasiuk, T. S. Brytanova, Ye. H. Knysh
Опубликовано 2019-12-01The purpose of work is the analysis of the range of dietary supplements of the modern pharmaceutical market of Ukraine on the basis of medicinal plant raw materials that affect the respiratory system. Materials and methods. The materials of the study included: regulatory documents, sources of sci...
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Synthesis and properties of bis((4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)alkanes по O. A. Suhak, O. I. Panasenko, Ye. H. Knysh
Опубликовано 2018-08-01The aim of this work was the synthesis of bis((4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)alkanes using available reagents and study of their properties. Matherial and methods. 4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-thiol was used as an intermediate compound, obtained from met...
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SYNTHESIS AND PHYSICAL-CHEMICAL PROPERTIESOF 3-ARIL-2-((3-(3-FLUORPHENYL)-1,2,4-TRIAZOLE-5-YL)THIO)PROP-2-EN-1-OLES по O. A. Bigdan, O. I. Panasenko, Ye. H. Knysh
Опубликовано 2015-04-01Modern scientific schools, which search for new biologically active substances of synthetic nature, pay special attention to synthetic heterocyclic systems with nitrogenatom. Among these heterocyclic compounds, the derivatives of 1,2,4-triazole should be mentioned. Many publications of both domesti...
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Biologically oriented synthesis of medicines (BIODS) based on heterylpoxid 2,5- disubstituted 1,3,4-oxadiazoles (Part 1) по Yu. V. Karpenko, O. I. Panasenko, Ye. H. Knysh
Опубликовано 2020-08-01At the present stage of development of medical chemistry, many basic synthetic approaches to the synthesis of 1,3,4-oxadiazole structures are known, which are focused mainly on the principles of combinatorial chemistry with a wide range of biological activity. The aim of the work was searching, s...
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NMRAL1 as a Causal Factor in Postherpetic Neuralgia: A Proteome-Wide Mendelian Randomization Study по Ye H, Wang Y, Shi Y, Wu Y, Xu Q, Huang S
Опубликовано 2025-05-01Hong Ye,1,* Yiling Wang,2,* Yuechun Shi,1 Yuyu Wu,1 Qiuhan Xu,2 Songmin Huang1 1Xiangshan Hospital of TCM Medical and Health Group, Ningbo City, Zhejiang Province, People’s Republic of China; 2School of Medicine, Zhejiang University, Hangzhou City, Zhejiang Province, People’s...
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PROPERTIES OF NEW SALTS OF 2-(5-(ADAMANTANE-1-YL)-4-R-1,2,4-TRIAZOLE-3-YLTIO)ACETIC ACIDS IN THE GLUCOSE TOLERANCE TEST по V. M. Odyntsova, Ye. S. Pruhlo, O. I. Panasenko, Ye. H. Knysh
Опубликовано 2015-04-01The concentration of glucose in the blood is one of the integral indicators of the internal environment that reflects the metabolism of carbohydrates, proteins and fats in the body. Glucose is a key component of human metabolism. The level of blood sugar is one of the most important controlled const...
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Synthesis and physical-chemical properties of 2-((4-R-3-(morpholinomethylen)-4H-1,2,4-triazole-5yl)thio)acetic acid по R. О. Shcherbyna, O. I. Panasenko, Ye. H. Knysh, B. О. Varynskyy
Опубликовано 2014-12-01The creation and improvement of the original domestic medicines is anactual problem of medical and pharmaceutical industries. Chemistry of heterocyclicsystems attracts scientists all over the world, as it is associated with a number of properties of this class of compounds which allow to use them fo...
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Comprehensive Review on Personalized Pain Assessment and Multimodal Interventions for Postoperative Recovery Optimization по Xu J, Liu X, Zhao J, Zhao J, Li H, Ye H, Ai S
Опубликовано 2025-06-01Jingying Xu,1,* Xiaona Liu,1,* Jinyan Zhao,1 Jingjing Zhao,2 Hao Li,1 Huanhuan Ye,2 Shuang Ai2 1Department of Rehabilitation Medicine, Joint Logistics Support Force No. 964 Hospital of People’s Liberation Army of China, Changchun, Jilin, 130000, People’s Republic of China; 2D...
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Round-Sharp Needle for Limb Spasms After a Stroke: Study Protocol for a Randomized Controlled Trial по Ye H, Liu J, Cheng H, He Y, Li C, Gao Y, Xu X
Опубликовано 2025-06-01Hongkun Ye,1 Jiahui Liu,1 Hongmei Cheng,1 Yu He,1 Chongrui Li,1 Yahan Gao,2 Xinyin Xu3– 5 1College of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan City, Hubei Province, People’s Republic of China; 2Department of Research, Hubei Provincial Hospital of Traditional Chinese M...
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