Search Results - Yanwen Wang

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  1. 1
    A dissimilarity-adaptive cross-validation method for evaluating geospatial machine learning predictions with clustered samples

    A dissimilarity-adaptive cross-validation method for evaluating geospatial machine learning predictions with clustered samples by Yanwen Wang, Mahdi Khodadadzadeh, Raúl Zurita-Milla

    Published 2025-12-01

    Spatially clustered samples are prevalent in geospatial machine learning (ML) predictions, especially in ecological mapping. Since densely sampled regions in the prediction area are overrepresented, leading to dissimilarities in the data distribution between samples and predictions and thus posing a...

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  2. 2
    Intranasal Administration of Cold-Adapted Live-Attenuated Eurasian Avian-like H1N1 Vaccine Candidate Confers Protection Against Different-Lineage H1N1 Viruses in Mice

    Intranasal Administration of Cold-Adapted Live-Attenuated Eurasian Avian-like H1N1 Vaccine Candidate Confers Protection Against Different-Lineage H1N1 Viruses in Mice by Qiu Zhong, Zuchen Song, Fei Meng, Yanwen Wang, Yijie Zhang, Zijian Feng, Yali Zhang, Yujia Zhai, Yan Chen, Chuanling Qiao, Hualan Chen, Huanliang Yang

    Published 2025-05-01

    Background/Objectives: Eurasian avian-like (EA) H1N1 swine influenza viruses, with their persistent evolution and zoonotic potential, seriously threaten both swine and human health. The objective was to develop an effective vaccine against these viruses. Methods: A cold-adapted, temperature-sensitiv...

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  3. 3
    Glutamic Acid at Position 343 in PB2 Contributes to the Virulence of H1N1 Swine Influenza Virus in Mice

    Glutamic Acid at Position 343 in PB2 Contributes to the Virulence of H1N1 Swine Influenza Virus in Mice by Yanwen Wang, Qiu Zhong, Fei Meng, Zhang Cheng, Yijie Zhang, Zuchen Song, Yali Zhang, Zijian Feng, Yujia Zhai, Yan Chen, Chuanling Qiao, Huanliang Yang

    Published 2025-07-01

    The H1N1 swine influenza viruses CQ91 and CQ445, isolated from pigs in China, exhibited distinct virulence in mice despite sharing similar genomic constellations. CQ91 demonstrated higher pathogenicity (MLD<sub>50</sub>: 5.4 log<sub>10</sub> EID<sub>50</sub>) and...

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  4. 4
    Pectinase responsive nanoplatform for oral targeted delivery 5-aminosalicylic acid and zinc coordination driven nanozyme in inflammatory bowel disease treatment

    Pectinase responsive nanoplatform for oral targeted delivery 5-aminosalicylic acid and zinc coordination driven nanozyme in inflammatory bowel disease treatment by Yiting Lin, Siqi Fang, Xinyi Chen, Xiang Li, Xinlin Zhao, Yanwen Wang, Jing Lu, Qingdong Ji, Shuhui Zheng, Jiafeng Zou, Chendong Qi, Feng Gao

    Published 2025-12-01

    Characterized by weight loss, intestinal ulcerations, and diarrhea with blood or mucus, inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is a chronic gastrointestinal condition. The rising incidence of IBD is placing pressure on healthcare systems globall...

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  5. 5
    Artesunate improves cryopreserved yak sperm quality by activating SOD1 antioxidant pathway

    Artesunate improves cryopreserved yak sperm quality by activating SOD1 antioxidant pathway by Yilin Fan, Yilin Fan, Weibing Lv, Weibing Lv, Xiaowei Li, Geri Wanma, Geri Wanma, Jian Li, Jian Li, Xianrong Xiong, Xianrong Xiong, Xiaoqiang He, Yanwen Wang, Shi Yin, Shi Yin, Wei Fu, Wei Fu, Honghong He, Honghong He, Yaqiu Lin, Yaqiu Lin, Daoliang Lan, Daoliang Lan, Yan Xiong, Yan Xiong

    Published 2025-06-01

    IntroductionSperm damage from oxidative stress is common in semen cryopreservation. Natural antioxidants for frozen semen are largely unexplored. Artesunate (ART), derived from Artemisia annua and used for malaria treatment, shows potential as a frozen semen antioxidant.MethodsWe investigated the ef...

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