Search Results - Yanwei Li
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FN1 from cancer-associated fibroblasts orchestrates pancreatic cancer metastasis via integrin-PI3K/AKT signaling
Published 2025-07-01Get full textObjectiveThe metastasis of pancreatic ductal adenocarcinoma (PDAC) is closely linked to the remodeling of cancer-associated fibroblasts (CAFs) within the tumor microenvironment (TME), though the precise molecular mechanisms remain unclear. This study aims to elucidate the role of CAFs in PDAC metast...
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The evolutionary characteristics and driving factors of the coupling coordination degree of digital economy and cultivated land use efficiency in China
Published 2025-07-01Get full textThe coupled and coordinated interaction between digital economy and cultivated land use efficiency (CLUE) is of great practical significance for guaranteeing national food security. Therefore, this study constructed the evaluation index system from two aspects of digital economy and CLUE, and used t...
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Long-read sequencing transforms the diagnosis of congenital adrenal hyperplasia: resolving pseudogene interference and structural variations
Published 2025-06-01Get full textBackgroundCongenital adrenal hyperplasia (CAH) is an autosomal recessive disorder primarily caused by defects in adrenal steroidogenesis. Conventional genetic methods struggle to resolve complex structural variations and pseudogene interference in key genes like CYP21A2. Our study will evaluate the...
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The Effects of Dietary Supplementation of Chestnut Tannic Acid on the Growth Performance, Gut Morphology and Microbiota of Weaned Piglets
Published 2025-07-01Get full text<b>Background/Objectives</b>: This study investigated the effects of chestnut tannic acid (TA) on the growth performance, the expression of tight junction proteins and the composition of the gut microbiota of weaned piglets, which could provide novel insights into the application of TA i...
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Alantolactone induces apoptosis through ROS-mediated AKT pathway and inhibition of PINK1-mediated mitophagy in human HepG2 cells
Published 2019-12-01Get full textAlantolactone (Ala), a major sesquiterpene lactone extracted from Inula helenium, exerts potent anti-tumour activities in various cancers. However, the underlying mechanism of such activities is still ambiguous. This study focused on evaluating the anti-tumour effects and molecular mechanisms of Ala...
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